Can a clever tether guide a child's curved spine straight as they grow?
NCT ID NCT07727408
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests a new surgical technique called active apex correction for children under 10 with early onset scoliosis. Instead of fusing the spine, the surgery uses screws and rods to tether the curve's outer side and guide the inner side, allowing the spine and lungs to keep growing. Researchers will measure changes in the spinal curve and growth on X-rays to see if the approach safely corrects the deformity without stopping development.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a surgical procedure called active apex correction that tethers the convex side of the spinal curve and modulates the concave side, using screws and rods that allow the spine to keep growing
- What this could lead to
- If it works, this technique could offer young children with scoliosis a way to correct their spinal curve while still allowing the spine and lungs to grow naturally, avoiding the need for fusion surgery.
- What could go wrong
- This is a very small, early trial with only 15 children, so results may not apply widely. The surgery is new and carries risks such as implant failure, nerve injury, or the need for additional procedures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 year to 10 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients with early-onset scoliosis below 10 years * patients not operated on before. Exclusion Criteria: * Patients above 10 years. * Patients operated on before
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Al-Azhar University Hospital, Assiut
RECRUITINGAsyut, Asyut Governorate, 71524, Egypt