Acne clue found in blood fats?
NCT ID NCT07250880
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will measure three types of fats (ceramides and S1P) in the blood of 40 people with acne and 40 healthy volunteers. The goal is to see if these fats are different in acne patients and if they relate to acne severity. No treatment is given—just a blood draw. The results may help scientists understand acne better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help explain how certain fats in the blood relate to acne, possibly pointing to new ways to diagnose or treat it.
- What could go wrong
- This is an early observational study with only 80 people. It measures substances in the blood, not a treatment, so it may not lead to any direct benefit for patients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study Population: A. Inclusion Criteria: For Case Group This group will consist of (40) patients : * Both males and females aged 15-40 years. * Mild, Moderate, severe and very severe cases will be included. 5 For Control Group: • This group will consist of age- and sex-matched (40) healthy volunteers. B. Exclusion Criteria (for both groups): * Presence of any dermatological condition other than acne vulgaris (for cases). * Use of systemic or topical treatment such as isotretinoin or antibiotics within the last 3 months. * Pregnancy or lactation. * History of lipid-lowering therapy or supplements affecting ceramide or sphingolipid metabolism
- Ages
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15 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * For Case Group This group will consist of (40) patients : * Both males and females aged 15-40 years. * Mild, Moderate, severe and very severe cases will be included. 5 For Control Group: • This group will consist of age- and sex-matched (40) healthy volunteers. Exclusion Criteria: * Presence of any dermatological condition other than acne vulgaris (for cases). * Use of systemic or topical treatment such as isotretinoin or antibiotics within the last 3 months. * Pregnancy or lactation. * History of lipid-lowering therapy or supplements affecting ceramide or sphingolipid metabolism.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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