New pill shows promise for ulcerative colitis in major trial
NCT ID NCT05507216
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 2 times
Summary
This study tested a new daily pill, ABX464, for people with moderate to severe ulcerative colitis who did not get better with other treatments. About 636 adults and teens took either 25 mg, 50 mg, or a placebo for 8 weeks. The main goal was to see if the drug could help achieve remission, meaning fewer symptoms and less inflammation in the colon.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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636 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Jul 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men or women at least 16 years old; Adolescent subjects will only be enrolled if approved by the country regulatory/health authority. If these approvals have not been granted, only subjects ≥ 18 years old will be enrolled. To be eligible, adolescent subjects must weigh ≥ 40 kg and meet the definition of Tanner Stage 5 at the screening visit. * Subjects must understand, sign and date the written voluntary informed consent form at the visit prior to any protocol-specific procedures. For under-aged subjects, national requirements regarding consent should also be met. * Documented diagnosis of UC confirmed by endoscopy and histology. Should endoscopy/histology results not be available at screening, results from endoscopies and biopsies taken at screening may be used. * Active disease defined by modified Mayo score (MMS) ≥ 5 with rectal bleeding subscore (RBS) ≥ 1 and endoscopy subscore (MES) of 2 or 3 (confirmed by central reader). * Subjects with documented inadequate response (defined as lack of response or loss of response or intolerance) to at least one of the following treatments: corticosteroids, immunosuppressant, biologic or biosimilar therapies, S1P receptor modulators and/or JAK inhibitors and/or new drugs approved during the study (note: failure to only 5-ASA or sulfasalazine is not accepted). * Women of childbearing potential (WOCBP) subjects and male subjects with WOCBP partner must agree to comply with the contraception requirements described in the protocol. * Subjects able and willing to comply with study visits and procedures as per protocol. * Subjects should be affiliated to a health insurance policy whenever required by a participating country or state. Exclusion Criteria: * Subjects with UC limited to an isolated proctitis (≤ 15cm from anal verge) determined by endoscopy central reading. * Subjects with primary sclerosing cholangitis or autoimmune hepatitis. * Subjects who have failed on 5-ASA or sulfasalazine therapy only. * Subjects with CD or presence or history of fistula, indeterminate colitis, infectious/ischemic colitis or microscopic colitis (lymphocytic and collagenous colitis). * History or current evidence of toxic megacolon, fulminant colitis, bowel perforation. * History of colonic cancer or colonic low grade or high grade dysplasia adenomatous polyps, and/or at the screening endoscopy, evidence of colonic cancer or evidence of low grade or high grade dysplasia adenomatous polyps (fully removed or not). * Recent or planned bowel surgery or history of proctocolectomy or partial colectomy or current stoma. * Subjects on antidiarrheals including those working on motility (e.g., loperamide, diphenoxylate with atropine, etc.). * Subjects on probiotics (e.g., Culturelle® \[Lactobacillus GG, i-Health, Inc.\], Saccharomyces boulardii). * Subjects who do not meet the washout period requirements prior to the screening endoscopy. * Subjects with the following hematological and biochemical laboratory parameters obtained during the screening period: * Hemoglobin ≤ 8.0 g dL-1 * Absolute neutrophil count \< 750 mm-3 * Platelets \< 100,000 mm-3 * Creatinine clearance \< 60 mL.min-1 (Cockroft-Gault formula) * Total serum bilirubin \> 1.5 x ULN * Alkaline phosphatase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) \> 2 x ULN * Subjects with the following conditions (infection): * Subjects with chronic or recurrent grade 3 or grade 4 infection within the last 2 months prior to screening or a history of opportunistic infection while not on immunosuppressive therapy. * Herpes zoster reactivation within the last 2 months prior to screening. * Subjects with active infection at screening or any major episode of infection that required hospitalization or treatment with intravenous antibiotics within 1 month of screening or during screening. Fungal infection of nail beds is allowed. * Positive assay or stool culture for pathogens (ova and parasite examination, bacteria) or positive test for Clostridium difficile toxin at screening. If C. difficile is positive, subject may be treated and retested ≥ 2 weeks after completing treatment. * Subjects with HIV infection. * Subjects having acute or chronic hepatitis B infection at screening (positive for hepatitis B surface antigen \[HbsAg\], or negative for HbsAg and positive for anti-hepatitis B core antibody in conjunction with detectable HBV DNA, or detectable HBV DNA). * Subjects having acute or chronic hepatitis C infection at screening as defined by positive for hepatitis C antibody (subjects successfully treated and without recurrence ≥ 1 year with no detectable HCV RNA \[assessed centrally\] are eligible). * Active tuberculosis (TB) or untreated latent TB are ruled out. For subjects with positive or intermediate QuantiFERON test see the current study protocol. * Subjects with an uncontrolled ischemic heart disease and/or a history of congestive heart failure with New York Heart Association (NYHA) class 3 or 4 symptoms. * Subjects with a family or personal history of congenital or acquired long QT syndrome, or subjects with a marked baseline prolongation of QT/QTc interval (e.g., repeated demonstration of a QTc interval \[Fridericia or Bazett correction\] \>450 milliseconds for male and \> 460 milliseconds for female). * Subjects with a history of torsade de pointe (TdP). * Acute or chronic of clinically relevant pulmonary, hepatic, pancreatic or renal functional abnormality, encephalopathy, neuropathy or unstable central nervous system pathology such as seizure disorder, or any other clinically significant medical problems as determined by physical examination and/or laboratory screening tests and/or medical history (note: treated autoimmune hypothyroidy and autoimmune diabetes are allowed). * Serious illness requiring hospitalization within 4 weeks prior to screening (except UC flare). * Subjects previously treated with ABX464. * Subjects with a known hypersensitivity to the active substance or to any of the excipients. * WOCBP subject who is pregnant or breast-feeding at screening, or intends to become pregnant during the study, or male subject with WOCBP partner who intends to be pregnant during the study. * Illicit drug or alcohol abuse or dependence. * Subjects who received live vaccine within 3 months prior to screening and/or who's planning to receive such a vaccine during the study duration. * Use of any investigational or non-registered product within 3 months or within 5 half-lives preceding baseline, whichever is longer, and during the study. * Subjects committed to an institution by virtue of an order issued either by the judicial or the administrative authorities. * Any condition, which in the opinion of the investigator, could compromise the subject's safety or adherence to the study protocol.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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(G.I.R.I.) GI Research Institute
Vancouver, British Columbia, V6Z 2K5, Canada
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1 Wojskowy Szpital Kliniczny z Polikliniką SPZOZ w Lublinie
Lublin, 20-049, Poland
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ALLMEDICA sp. z o. o.
Nowy Targ, 34-400, Poland
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AZ Delta
Roeselare, 8800, Belgium
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AZ Maria Middelares
Ghent, 9000, Belgium
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Accelerium S de RL de CV
Monterrey, Nuevo León, 64000, Mexico
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Accout Center s.r.o.
Šahy, 93601, Slovakia
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Acibadem City Clinic Mladost Eood
Sofia, Bulgaria
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Addenbrooke's Hospital
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
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Advanced Medical Research Center
Port Orange, Florida, 32127, United States
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AdventHealth Medical Group
Orlando, Florida, 32804, United States
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All India Institute of Medical Sciences
New Delhi, National Capital Territory of Delhi, 110029, India
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Aoyama Clinic
Kobe, Hyōgo, 650-0015, Japan
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Applied Research Center of Arkansas
Little Rock, Arkansas, 72212, United States
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Arnold Palmer Hospital For Children
Orlando, Florida, 32806, United States
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Asahikawa City Hospital
Asahikawa-shi, Japan
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Asahikawa Medical University Hospital
Asahikawa-shi, Japan
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Aso Co.,Ltd Iizuka Hospital
Iizuka-shi, Fukuoka, 820-8505, Japan
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Azienda Ospedale-Università di Padova
Padova, Italy
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Azienda Ospedaliero Universitaria Mater Domini
Catanzaro, 88100, Italy
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Azienda Socio Sanitaria Territoriale Fatebenefratelli (Presidio Ospedale Sacco)
Milan, 20157, Italy
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BVL Clinical Research
Liberty, Missouri, 64068, United States
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Beaumont Hospital
Dublin, Ireland
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CDC - Centro Digestivo de Curitiba
Curitiba, Paraná, 80430-160, Brazil
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CECIP - Centro de Estudos Clínicos do Interior Paulista
Jaú, São Paulo, 17201-130, Brazil
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CEMIC
Buenos Aires, Ciudad Autonoma Buenos Aires, 1431, Argentina
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CHU Amiens - Hopital Sud
Amiens, Somme, 80054, France
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CHU Lille - Hôpital Claude Huriez
Lille, Nord, 59037, France
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CHU Nice - Hôpital de l'Archet 2
Nice, Alpes Maritimes, 06200, France
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CHU Rennes - Hôpital Pontchaillou
Rennes, Ille Et Vilaine, 35000, France
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CHU de Grenoble - Hôpital Nord
Grenoble, Isere, 38043, France
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CNCE M.I.Pyrohov Vinnytsia Regional Clinical Hospital of Vinnytsia Regional Council
Vinnytsia, Ukraine
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CNCE Vinnytsia City Clinical Hospital #1, Dep of Clinical Therapy #2
Vinnytsia, Ukraine
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CNCE of Kyiv Regional Council Kyiv Regional Center of Rehabilitation Medicine
Kyiv, Ukraine
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CNCE of Kyiv Regional Council Kyiv Regional Clinical Hospital, Clinical Center of Therapeutic Profil
Kyiv, Ukraine
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CNCE of Lviv Regional Council Lviv Regional Clinical Hospital
Lviv, Ukraine
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CNE A.Novak Transcarpathian Reg Clin Hospital of Transcarpathian Reg Council
Uzhhorod, Ukraine
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CNE Odesa Regional Clinical Hospital of Odesa Regional Council
Odesa, Ukraine
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Carmel Medical Center
Haifa, 34362, Israel
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Centre Hospitalier Départemental Les Oudairies
La Roche-sur-Yon, Vendée, 85925, France
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Centre Hospitalier Lyon Sud
Pierre-Bénite, Rhone, 69495, France
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Centro Medico Teknon
Barcelona, 08022, Spain
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Centro de Investigacion CICE
San Miguel de Tucumán, Tucumán Province, 4000, Argentina
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Centro de Investigaciones Clinicas Baigorria
Rosario, Santa Fe Province, Argentina
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Centro de Investigaciones Medicas Tucuman
San Miguel de Tucumán, Tucumán Province, T4000AXL, Argentina
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Centrum Medyczne Plejady
Krakow, 30-363, Poland
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Centrum Medyczne Plejady
Krakow, Poland
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Centrum Medyczne Pratia Gdynia
Gdynia, 81-338, Poland
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Centrum Zdrowia Tuchow Sp. z o.o.
Wierzchosławice, 33-122, Poland
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Chaim Sheba Medical Center
Ramat Gan, 5265602, Israel
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Charité - Campus Charité Mitte
Berlin, 10117, Germany
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Citrus Valley Gastroenterology
Covina, California, 91723, United States
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Cliagen - Clinica de Atencao em Gastroenterologia, Especialidades e Nutricao
Salvador, Estado de Bahia, Brazil
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Clinfan Szolgaltato Kft.
Szekszárd, 7100, Hungary
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Clinical Applications Laboratories
San Diego, California, 92103, United States
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Clinical Center " Dr Dragisa Misovic Dedinje"
Belgrade, 11000, Serbia
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Clinical Hospital Center "Bezanijska kosa
Belgrade, Serbia
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Clinical Hospital Center Zvezdara
Belgrade, 11000, Serbia
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Clinical Research Institute of Michigan, LLC
Chesterfield, Michigan, 48047, United States
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Cliniq s.r.o.
Bratislava, 82007, Slovakia
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Communal Enterprise Hospital #1 of Zhytomyr City Council
Zhytomyr, Ukraine
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Communal Enterprise Volyn Regional Clinical Hospital of Volyn Regional Council
Lutsk, Ukraine
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Complejo Hospitalario Universitario de Ferrol
Ferrol, La Coruña, 15405, Spain
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Connolly Hospital
Abbotstown, Dublin, D15 X40D, Ireland
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Consultorio Medico, InvesclinicMX
Irapuato, Guanajuato, 36650, Mexico
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Cotton O'Neil Clinical Research Center
Topeka, Kansas, 66606, United States
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DC-MED
Swidnica, 58-100, Poland
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DIM Clinica Privada
Ramos Mejía, Buenos Aires, Argentina
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DRK Kliniken Berlin Westend
Berlin, 14050, Germany
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Danbury Hospital
Danbury, Connecticut, 06810, United States
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Datta Meghe Institute of Medical Sciences (Deemed University)
Wardha, Maharashtra, 442004, India
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Diagnostic Consultation Center CONVEX EOOD
Sofia, 1680, Bulgaria
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Digestive Health Research, LC
Hermitage, Tennessee, 37076, United States
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Digestive System Healthcare
Pasadena, Texas, 77505, United States
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ETG Kielce Zagorska
Kielce, 25-355, Poland
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Ehime Prefectural Central Hospital
Matsuyama, Ehime, 790-0024, Japan
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Endomed, s.r.o.
Košice, 04013, Slovakia
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Evangelisches Krankenhaus Kalk GmbH
Cologne, Germany
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FAICIC S. de R.L. de C.V.
Veracruz, 91900, Mexico
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Fakultna nemocnica s poliklinikou F.D. Roosevelta
Banská Bystrica, 97517, Slovakia
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, 00168, Italy
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Fortis Escorts Heart Institute and Research Centre
New Delhi, National Capital Territory of Delhi, 110025, India
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Frontier Clinical Research, LLC
Uniontown, Pennsylvania, 15401, United States
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Fukui Prefectural Hospital
Fukui-shi, Japan
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Fukuoka University Chikushi Hospital
Chikushino-shi, Fukuoka, 818-8502, Japan
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GCP Clinical Research, LLC
Tampa, Florida, 33609, United States
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GZA Ziekenhuizen
Antwerp, 2018, Belgium
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Gabinet Lekarski Bartosz Korczowski
Rzeszów, 35-302, Poland
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Galilee Medical Center Institute of Gastroenterology
Nahariya, Israel
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Gandhi Hospital
Secunderabad, Andhra Pradesh, 500003, India
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Gastro I, s.r.o.
Prešov, 08001, Slovakia
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Gastro LM s.r.o.
Prešov, 08001, Slovakia
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Gastroenterology Consultants and Endoscopy Center of Southwest Virginia
Roanoke, Virginia, 24014, United States
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Gastroenterology Consultants of South Texas, PA
Harlingen, Texas, 78550, United States
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Gastroenterología Diagnóstica y Terapéutica (Gedyt)
Ciudad Autonoma Buenos Aires, C1117ABK, Argentina
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General Hospital "Djordje Joanovic"
Zrenjanin, Serbia
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General Hospital Prim.dr.Abdulah Nakas
Sarajevo, Bosnia and Herzegovina
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General Hospital Subotica
Subotica, 24000, Serbia
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Gleneagles Global Hospitals
Hyderabad, India
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Gordon and Leslie Diamond Health Care Centre - Vancouver General Hospital
Vancouver, British Columbia, Canada
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Gujarat Hospital
Surat, Gujarat, 395009, India
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Guy's Hospital
London, Greater London, SE1 9RT, United Kingdom
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Gyongyosi Bugat Pal Korhaz
Gyöngyös, 3200, Hungary
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HUWC - UFC - Hospital Universitário Walter Cantídio - Universidade Federal do Ceará
Fortaleza, Ceará, 60430-370, Brazil
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HaEmek Medical Center
Afula, 18101, Israel
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Hamburgisches Forschungsinstitut fure Chronische Darmerkrankungen
Hamburg, 20251, Germany
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Hepatogastro
São Paulo, São Paulo, 04543-011, Brazil
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Hoag Memorial Hospital Presbyterian
Newport Beach, California, 92663, United States
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Hopital Rangueil
Toulouse, Haute Garonne, 31059, France
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Hospital Aliança
Salvador, Estado de Bahia, 41920-180, Brazil
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Hospital Britanico de Buenos Aires
Buenos Aires, Ciudad Autonoma Buenos Aires, C1280AEB, Argentina
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Hospital Clinico Universitario de Valencia
Valencia, 46010, Spain
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Hospital General Juan Ramon Jimenez
Huelva, 21005, Spain
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Hospital Montecelo
Pontevedra, 36071, Spain
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Hospital Sirio Libanes
São Paulo, Brazil
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Hospital Universitario Miguel Servet
Zaragoza, 50009, Spain
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Hospital Universitario de Fuenlabrada
Fuenlabrada, Madrid, 28942, Spain
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Hospital Universitario de Gran Canaria Dr. Negrin
Las Palmas de Gran Canaria, Las Palmas, 35019, Spain
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Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil
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Hospital de brabois
Vandœuvre-lès-Nancy, Moselle, 57070, France
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Hospital of Lithuanian University of Health Sciences Kaunas Clinics
Kaunas, LT-50161, Lithuania
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Hyogo Prefectural Harima-Himeji General Medical Center
Himeji-shi, Japan
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Hôpital Nord - CHU Marseille
Marseille, Bouches-du-Rhône, 13915, France
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IHS Health
Kissimmee, Florida, 34741, United States
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INLUGA im Haus der Gesundheit
Ludwigshafen am Rhein, Rhineland-Palatinate, 67067, Germany
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Indywidualna Specjalistyczna Praktyka Lekarska Maciej Zymla
Knurów, 44-190, Poland
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Inquest Clinical Research
Baytown, Texas, 77521, United States
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Institut des MICI
Neuilly, Hauts De Seine, 92200, France
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Institut klinicke a experimentalni mediciny
Prague, 14021, Czechia
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Institute of Post Graduate Medical Education And Research
Kolkata, West Bengal, 700020, India
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Institute of Science Tokyo Hospital
Bunkyō City, Japan
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Instituto de Pesquisas em Saúde - Fundação Universidade de Caxias do Sul (IPS/FUCS)
Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil
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Irmandade da Santa Casa da Misericórdia de Santos
Santos, São Paulo, 11075-101, Brazil
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Isha Multispeciality Hospital
Vadodara, Gujarat, 390007, India
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Istituto Clinico Humanitas
Rozzano, Milano, 20089, Italy
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JCHO Hokkaido Hospital
Sapporo, Hokkaido, 062-8618, Japan
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JCHO Osaka Hospital
Osaka, Osaka, 553-0003, Japan
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JCHO Tokyo Yamate Medical Center
Shinjuku-ku, Tokyo-To, 169-0073, Japan
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Jiaikai Izuro Imamura Hospital
Kagoshima, Kagoshima-ken, 892-0824, Japan
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Juntendo University Hospital
Bunkyō City, Japan
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KM Management spol. s r.o.
Nitra, 04901, Slovakia
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Kagawa Prefectural Central Hospital
Takamatsu, Kagawa-ken, 760-8557, Japan
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Kagoshima IBD Gastroenterology Clinic
Kagoshima, Kagoshima-ken, 892-0843, Japan
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Kaiseikai Hattori Clinic
Kumamoto, Kumamoto, 860-0004, Japan
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Kaplan Medical Center KMC Institute of Gastroenterology and Liver Diseases
Rehovot, 76100, Israel
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Kawasaki Municipal Hospital
Kawasaki-shi, Kanagawa, 210-0013, Japan
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Keiaikai Nakagami Hospital
Okinawa-shi, Okinawa, 904-2195, Japan
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Keijinkai Matsushima Hospital
Yokohama, Japan
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Kiryu Kosei General Hospital
Kiryu-shi, Gunma, 376-0024, Japan
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Kitasato University Kitasato Institute Hospital
Minatoku, Tokyo-To, 108-8642, Japan
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Kokikai Tsujinaka Hospital Kashiwanoha
Kashiwa-shi, Chiba, 277-0871, Japan
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Krankenhaus Waldfriede e. V.
Berlin, 14163, Germany
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Kumagaya General Hospital
Kumagaya-shi, Saitama, 360-8567, Japan
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Kurume University Hospital
Kurume-shi, Fukuoka, 830-0011, Japan
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Kyorin University Hospital
Mitaka-shi, Japan
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L2IP - Instituto de Pesquisas Clínicas Ltda.
Brasília, Federal District, 70200-730, Brazil
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LinQ Research, LLC
Pearland, Texas, 77584, United States
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Lithuanian University of Health Sciences Kaunas Hospital
Kaunas, 47144, Lithuania
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Lokmanya Tilak Municipal General Hospital & Medical College
Mumbai, Maharashtra, 400022, India
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London Health Sciences Centre (LHSC) - Victoria Hospital
London, Canada
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M.V. Sklifosovskyi Poltava RCH Dept of Pulmonology HSEIU Ukrainian Medical Stomatological Academy
Poltava, Ukraine
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MC Medica Plus
Veliko Tarnovo, 5000, Bulgaria
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Maharaja Agrasen Hospital
New Delhi, National Capital Territory of Delhi, 110026, India
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Matsuaikai Matsuda Hospital
Hamamatsu, Shizuoka, 432-8061, Japan
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Medical Center Universal Clinic Oberih of Limited Liability Company Kapital
Kyiv, Ukraine
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Medical Center of Limited Liability Company Arensia Exploratory Medicine
Kyiv, Ukraine
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Medical Center of Limited Liability Company Medical Center Clinic of Family Medicine
Dnipro, Ukraine
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Medicome Sp. z o.o.
Oświęcim, 32-600, Poland
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Meir Medical Center
Kfar Saba, 4428164, Israel
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Midland Regional Hospital
Mullingar, Westmeath, N91, Ireland
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Mount Sinai
New York, New York, 10029, United States
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NHI Komatsu Municipal Hospital
Komatsu-shi, Japan
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NHO Fukuyama Medical Center
Fukuyama-shi, Hiroshima, 720-8520, Japan
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NHO Hirosaki General Medical Center
Hirosaki-shi, Japan
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NHO Kanazawa Medical Center
Kanazawa, Ishikawa-ken, 920-8650, Japan
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NHO Kure Medical Center and Chugoku Cancer Center
Kure-shi, Hiroshima, 737-0023, Japan
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NHO Okayama Medical Center
Okayama, Okayama-ken, 701-1192, Japan
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NHO Osaka National Hospital
Osaka, Osaka, 540-0006, Japan
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NHO Ureshino Medical Center
Ureshino-shi, Saga-ken, 843-0393, Japan
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NY Scientific Corp.
Brooklyn, New York, 11235, United States
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NZOZ Centrum Medyczne KERmed
Bydgoszcz, 85-231, Poland
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NZOZ Neuromed M. i M. Nastaj Sp.P.
Lublin, Poland
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Nagaoka Red Cross Hospital
Nagaoka-shi, Japan
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National Institute of Clinical Research
Bakersfield, California, 93309, United States
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Newfoundland and Labrador Health Services
Winnipeg, Manitoba, Canada
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Nowe zdrowie-CK, Kieltucki i wspolnicy sp. j.
Staszów, 28-200, Poland
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Okayama University Hospital
Okayama, Okayama-ken, 700-8558, Japan
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Omega Research Orlando, LLC
Orlando, Florida, 32808, United States
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Origin Hospital
Hyderabad, Andhra Pradesh, 500048, India
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Osaka Medical and Pharmaceutical University Hospital
Takatsuki-shi, Japan
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Our Lady of the Snow St. Mary's Hospital
Kurume-shi, Fukuoka, 830-8543, Japan
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Pesquisare Saúde
Santo André, São Paulo, 09080-110, Brazil
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Plains Clinical Research Center, LLC
Fargo, North Dakota, 58104, United States
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Poliklinika Borzan d.o.o
Osijek, 31000, Croatia
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Portiuncula Hospital
Galway, Ireland
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Praxis Pesquisa Medica
Santo André, São Paulo, 09090-970, Brazil
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Premier Health Research
Sparta, New Jersey, 07871, United States
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RCNECRCH Dept of Proctology, SHEI Ukr BSMU
Chernivtsi, Ukraine
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Rabin Medical Center-Beilinson Campus
Petah Tikva, 4941492, Israel
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Railway Transport Kyiv Clinical Hospital #2 of Healthcare Center Branch of JSC Ukrainian Railway
Kyiv, Ukraine
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Rapid City Medical Center, LLC
Rapid City, South Dakota, 57701, United States
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Research Associates of South Florida
Miami, Florida, 33134, United States
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Research Solutions of Arizona, PC
Litchfield Park, Arizona, 85340, United States
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Richmond VA Medical Center
Richmond, Virginia, 23249, United States
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S.C Centrul Medical Valahia S.R.L
Ploieşti, 100550, Romania
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S.C Pelican Impex S.R.L
Oradea, 410469, Romania
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SC Centrul Medical Medicum SRL, Specialitatea Gastroenterologie
Bucharest, 012015, Romania
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SSH St. Panteleimon of MNPE "Lviv Territorial Med Union" MC of E&I care,Th. Center D.Halytskyi LNMU
Lviv, Ukraine
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SUBARU Health Insurance Society Ota Memorial Hospital
Ota-shi, Gunma, 373-8585, Japan
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Saga University Hospital
Saga, Saga-ken, 849-8501, Japan
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Saga-Ken Medical Centre Koseikan
Saga, Saga-ken, 840-8571, Japan
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Saiseikai Niigata Hospital
Niigata, Niigata, 950-1104, Japan
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Sameshima Hospital
Kagoshima, Kagoshima-ken, 892-0846, Japan
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Sanchez Clinical Research, Inc
Miami, Florida, 33157, United States
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Santa Maria Gastroenterology Medical Group
Santa Maria, California, 93458, United States
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Sarkis Clinical Trials - Parent
Ocala, Florida, 34474, United States
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Semmelweis Egyetem
Budapest, 1088, Hungary
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Shaare Zedek Medical Center
Jerusalem, 9103102, Israel
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Shinseikai Sai Gastroenterology, Proctology Clinic
Fujiidera, Osaka, 583-0027, Japan
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Showa University Koto Toyosu Hospital
Kōtoku, Tokyo-To, 135-8577, Japan
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Showa University Northern Yokohama Hospital
Yokohama, Kanagawa, 224-8503, Japan
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Siloah St. Trudpert Klinikum
Pforzheim, Germany
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Sociedad de Metabolismo y Corazon S.C
Veracruz, 91900, Mexico
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Somogy Varmegyei Kaposi Mor Oktato Korhaz
Kaposvár, 7400, Hungary
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Soroka University Medical Center
Beersheba, 84001, Israel
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Southern Star Research Institute, LLC
San Antonio, Texas, 78229, United States
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Spitalul Clinic Colentina
Bucharest, 020125, Romania
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Spitalul Clinic Judetean de Urgenta Cluj Napoca
Cluj-Napoca, 400006, Romania
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Spitalul de Oncologie Monza
Bucharest, 013812, Romania
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St Vincents University Hospital
Dublin, Ireland
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Surat Institute of Digestive Sciences
Surat, Gujarat, 395002, India
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Susquehanna Research Group, LLC
Harrisburg, Pennsylvania, 17110, United States
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Svet zdravia a.s.
Rimavská Sobota, 97901, Slovakia
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Takamatsu Red Cross Hospital
Takamatsu, Kagawa-ken, 760-0017, Japan
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Tandem Clinical Research, LLC
Marrero, Louisiana, 70072, United States
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Tel Aviv Sourasky Medical Center
Tel Aviv, Israel
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Texas Clinical Research Institute, LLC
Arlington, Texas, 76012, United States
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The University of Iowa
Iowa City, Iowa, 52242, United States
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The Vancouver Clinic
Vancouver, Washington, 98664, United States
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Tokyo Metropolitan Bokutoh Hospital
Sumida-ku, Japan
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Trialmed CRS
Piotrkow Trybunalski, 62-800, Poland
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Tyler Research Institute, LLC
Tyler, Texas, 75703, United States
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UNESP - Faculdade de Medicina da Universidade Estadual Paulista - Campus Botucatu
Botucatu, São Paulo, 18618-686, Brazil
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United Medical Doctors
Murrieta, California, 92563, United States
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Universitaetsklinikum Tuebingen
Tübingen, Baden-Wurttemberg, 72076, Germany
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Universitaetsklinikum Ulm
Ulm, Germany
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Universitair Ziekenhuis Gent
Ghent, 9000, Belgium
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University Clinical Center Kragujevac
Kragujevac, Serbia
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University Clinical Center Tuzla
Tuzla, Bosnia and Herzegovina
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University Clinical Centre of the Republic of Srpska
Banja Luka, Bosnia and Herzegovina
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University hospital centre Zagreb
Zagreb, 10000, Croatia
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University of Alabama -Birmingham
Birmingham, Alabama, 35205, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of South Florida - PARENT
Tampa, Florida, 33612, United States
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Università Campus Bio-Medico di Roma
Roma, 00128, Italy
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Vydehi Institute of Medical Sciences and Research Centre
Bengaluru, India
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Waikato Hospital
Hamilton, 3200, New Zealand
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Wellness Clinical Research
Miami Lakes, Florida, 33016, United States
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West Central Gastroenterology d/b/a Gastro Florida
Clearwater, Florida, 33762, United States
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Wojewodzki Specjalistyczny Szpital w Olsztynie
Olsztyn, 10-561, Poland
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Wolfson Medical Center
Holon, Israel
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Yashoda Super Speciality Hospital
Hyderabad, Andhra Pradesh, 500082, India
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