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New pill aims to tame ulcerative colitis Flare-Ups

NCT ID NCT05507203

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 11, 2026 · Updated 4 times

Summary

This study tested a once-daily pill called ABX464 (obefazimod) in 639 people with moderate-to-severe ulcerative colitis who had not responded well to other treatments. The goal was to see if the drug could help bring about remission and improve bowel inflammation within 8 weeks. The trial is now complete, and results will show whether this new option is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ABX464 (obefazimod), a once-daily pill
What this could lead to
If successful, this could provide a new once-daily treatment option to help control ulcerative colitis and reduce symptoms.
What could go wrong
This is a completed Phase 3 trial, but results are not yet published. It may not show a clear benefit over placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

639 people

The number who actually took part.

Started

Nov 2022

Finished

Jun 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men or women at least 16 years old; Adolescent subjects will only be enrolled if approved by the country regulatory/health authority. If these approvals have not been granted, only subjects ≥ 18 years old will be enrolled. To be eligible, adolescent subjects must weight ≥ 40 kg and meet the definition of Tanner Stage 5 at the screening visit. * Subjects must understand, sign and date the written voluntary informed consent form at the visit prior to any protocol-specific procedures. For under-aged subjects, national requirements regarding consent should also be met. * Documented diagnosis of UC confirmed by endoscopy and histology. Should endoscopy/histology results not be available at screening, results from endoscopies or biopsies taken at screening may be used. * Active disease defined by modified Mayo score (MMS) ≥ 5 with rectal bleeding subscore (RBS) ≥ 1 and endoscopy subscore (MES) of 2 or 3 (confirmed by central reader). * Subjects with documented inadequate response (defined as lack of response or loss of response or intolerance) to at least one of the following treatments: corticosteroids, immunosuppressant, biologic or biosimilar therapies, S1P receptor modulators and/or JAK inhibitors and/or new drugs approved during the study (note: failure to only 5-ASA or sulfasalazine is not accepted). * Women of childbearing potential (WOCBP) subjects and male subjects with WOCBP partner must agree to comply with the contraception requirements described in the protocol. * Subjects able and willing to comply with study visits and procedures as per protocol. * Subjects should be affiliated to a health insurance policy whenever required by a participating country or state. Exclusion Criteria: * Subjects with UC limited to an isolated proctitis (≤ 15cm from anal verge) determined by endoscopy central reading. * Subjects with primary sclerosing cholangitis or autoimmune hepatitis. * Subjects who have failed on 5-ASA or sulfasalazine therapy only. * Subjects with CD or presence or history of fistula, indeterminate colitis, infectious/ischemic colitis or microscopic colitis (lymphocytic and collagenous colitis). * History or current evidence of toxic megacolon, fulminant colitis, bowel perforation. * History of colonic cancer or colonic low grade or high grade dysplasia adenomatous polyps, and/or at the screening endoscopy, evidence of colonic cancer or evidence of low grade or high grade dysplasia adenomatous polyps (fully removed or not). * Recent or planned bowel surgery or history of proctocolectomy or partial colectomy or current stoma. * Subjects on antidiarrheals including those working on motility (e.g., loperamide, diphenoxylate with atropine, etc.). * Subjects on probiotics (e.g., Culturelle® \[Lactobacillus GG, i-Health, Inc.\], Saccharomyces boulardii). * Subjects who do not meet the washout period requirements prior to the screening endoscopy * Subjects with the following hematological and biochemical laboratory parameters obtained during the screening period: * Hemoglobin ≤ 8.0 g dL-1 * Absolute neutrophil count \< 750 mm-3 * Platelets \< 100,000 mm-3 * Creatinine clearance \< 60 mL.min-1 (Cockroft-Gault formula) * Total serum bilirubin \> 1.5 x ULN * Alkaline phosphatase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) \> 2 x ULN * Subjects with the following conditions (infection): * Subjects with chronic or recurrent grade 3 or grade 4 infection within the last 2 months prior to screening or a history of opportunistic infection while not on immunosuppressive therapy. * Herpes zoster reactivation within the last 2 months prior to screening. * Subjects with active infection at screening or any major episode of infection that required hospitalization or treatment with intravenous antibiotics within 1 month of screening or during screening. Fungal infection of nail beds is allowed. * Positive assay or stool culture for pathogens (ova and parasite examination, bacteria) or positive test for Clostridium difficile toxin at screening. If C. difficile is positive, subject may be treated and retested ≥ 2 weeks after completing treatment. * Subjects with HIV infection. * Subjects having acute or chronic hepatitis B infection at screening (positive for hepatitis B surface antigen \[HbsAg\], or negative for HbsAg and positive for anti-hepatitis B core antibody in conjunction with detectable HBV DNA, or detectable HBV DNA). * Subjects having acute or chronic hepatitis C infection at screening as defined by positive for hepatitis C antibody (subjects successfully treated and without recurrence ≥ 1 year with no detectable HCV RNA \[assessed centrally\] are eligible). * Active tuberculosis (TB) or untreated latent TB are ruled out. For subjects with positive or intermediate QuantiFERON test see study protocol. * Subjects with an uncontrolled ischemic heart disease and/or a history of congestive heart failure with New York Heart Association (NYHA) class 3 or 4 symptoms. * Subjects with a family or personal history of congenital or acquired long QT syndrome, or subjects with a marked baseline prolongation of QT/QTc interval (e.g., repeated demonstration of a QTc interval \[Fridericia or Bazett correction\] \>450 milliseconds for male and \> 460 milliseconds for female). * Subjects with a history of torsade de pointe (TdP). * Acute or chronic of clinically relevant pulmonary, hepatic, pancreatic or renal functional abnormality, encephalopathy, neuropathy or unstable central nervous system pathology such as seizure disorder, or any other clinically significant medical problems as determined by physical examination and/or laboratory screening tests and/or medical history (note: treated autoimmune hypothyroidy and autoimmune diabetes are allowed). * Serious illness requiring hospitalization within 4 weeks prior to screening (except UC flare). * Subjects previously treated with ABX464. * Subjects with a known hypersensitivity to the active substance or to any of the excipients. * WOCBP subject who is pregnant or breast-feeding at screening, or intends to become pregnant during the study, or male subject with WOCBP partner who intends to be pregnant during the study. * Illicit drug or alcohol abuse or dependence. * Subjects who received live vaccine within 3 months prior to screening and/or who's planning to receive such a vaccine during the study duration. * Use of any investigational or non-registered product within 3 months or within 5 half-lives preceding baseline, whichever is longer, and during the study. * Subjects committed to an institution by virtue of an order issued either by the judicial or the administrative authorities. * Any condition, which in the opinion of the investigator, could compromise the subject's safety or adherence to the study protocol.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AKH - Medizinische Universität Wien

    Vienna, 1090, Austria

  • AMICARE spółka z ograniczoną odpowiedzialnością spółka komandytowa

    Lodz, 90-644, Poland

  • AZ Sint-Lucas

    Bruges, 8310, Belgium

  • Access Research Institute

    Brooksville, Florida, 34613, United States

  • Acibadem Kozyatagi Hospital

    Istanbul, 34742, Turkey (Türkiye)

  • Advanced Research Institute, Inc.

    New Port Richey, Florida, 34653, United States

  • Advanced Research Institute, Inc.

    Orlando, Florida, 32825, United States

  • Amrita Institute Of Medical Sciences and Research Centre

    Kochi, Kerala, 682041, India

  • Amsterdam UMC, Locatie AMC

    Amsterdam, 1105 AZ, Netherlands

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Auzmer Research

    Lakeland, Florida, 33813, United States

  • Azienda Ospedaliera Giuseppe Brotzu

    Cagliari, 09134, Italy

  • Azienda Ospedaliera Ospedali Riuniti "Villa Sofia-Cervello"

    Palermo, 90146, Italy

  • Azienda Ospedaliero Universitaria Pisana (Presidio di Cisanello)

    Pisa, Italy

  • Baylor College Of Medicine

    Houston, Texas, 77030, United States

  • Baylor Scott and White

    Dallas, Texas, 75246, United States

  • Bekes Varmegyei Kozponti Korhaz

    Békéscsaba, 5600, Hungary

  • Bernhoven Uden

    Uden, 5406 PT, Netherlands

  • Binzhou Medical University Hospital

    Binzhou, Shandong, 256603, China

  • Biopharma Informatic, Inc. Research Center

    Houston, Texas, 77043, United States

  • Biopharma Informatic, LLC

    Houston, Texas, 77084, United States

  • Birmingham Digestive Health Research

    Homewood, Alabama, 35209, United States

  • Blue Ridge Medical Research

    Lynchburg, Virginia, 24502, United States

  • Box Hill Hospital

    Box Hill, Victoria, 3128, Australia

  • Bury Care Organisation

    Bury, Greater Manchester, BL9 7TD, United Kingdom

  • C. H. U. St-Pierre

    Brussels, 1000, Belgium

  • CCR Brno, s.r.o.

    Brno, 60200, Czechia

  • CCR Ostrava s.r.o.

    Ostrava, 70200, Czechia

  • CHU Besançon - Hôpital Jean Minjoz

    Besançon, Doubs, 25000, France

  • CHU Bordeaux - Hôpital Haut-Lévêque

    Pessac, Gironde, 33604, France

  • CHU Clermont Ferrand - Hopital d'Estaing

    Clermont-Ferrand, Puy De Dome, 63000, France

  • CHU Dijon - Hôpital Bocage Central

    Dijon, Cote D'or, 21000, France

  • CHU Nantes - Hôtel Dieu

    Nantes, Loire Atlantique, 44093, France

  • CHU Reims - Hôpital Robert Debré

    Reims, Ardennes, 51100, France

  • CHU Saint Etienne - Hôpital Nord

    Saint-Étienne-de-Montluc, Pays de la Loire Region, 42055, France

  • CHU UCL Namur

    Yvoir, 5530, Belgium

  • CNCE Khmelnytskyi Regional Hospital of Khmelnytskyi Regional Council

    Khmelnytskyi, 29000, Ukraine

  • CNCE Kyiv City Clinical Hospital #1 of Executive Body of Kyiv City Council

    Kyiv, 02091, Ukraine

  • CNCE of Lviv Regional Council Lviv Regional Clinical Hospital

    Lviv, Ukraine

  • CNE Cherkasy Regional Hospital of Cherkasy Regional Council

    Cherkasy, 18009, Ukraine

  • CNE M.I. Pyrohov Vinnytsia RCH of Vinnytsia Regional Council, RSC Gastro Center

    Vinnytsia, 21018, Ukraine

  • CNE Regional Clinical Hospital of Ivano-Frankivsk Regional Council

    Ivano-Frankivsk, 76008, Ukraine

  • CNE Uzhhorod city MCH of UCC Dept of Therapy

    Uzhhorod, 88000, Ukraine

  • California Medical Research Associates Inc.

    Northridge, California, 91324, United States

  • Canberra Hospital

    Canberra, Australian Capital Territory, 2605, Australia

  • Care Access Research LLC

    Ogden, Utah, 84403, United States

  • Care Access Research Lumberton

    Lumberton, North Carolina, 28358, United States

  • Central Texas Clinical Research, LLC

    Austin, Texas, 78705, United States

  • Centre Hospitalier de Pau - Hôpital François Mitterrand

    Pau, Pyrénées Atlantique, 64000, France

  • Centro Hospitalar de Entre o Douro e Vouga, E.P.E - Hospital de São Sebastião

    Santa Maria da Feira, 4520-211, Portugal

  • Centrum Medyczne Oporow

    Wroclaw, 52-416, Poland

  • Charité - Campus Benjamin Franklin

    Berlin, 12203, Germany

  • Charlotte Gastroenterology and Hepatology, P.L.L.C

    Charlotte, North Carolina, 28207, United States

  • Chhatrapati Shahuji Maharaj (CSM) Medical University

    Lucknow, Uttar Pradesh, 226003, India

  • Chopda Medicare & Research Centre

    Nashik, Maharashtra, 422005, India

  • Chung-Ang University Hospital

    Seoul, 06973, South Korea

  • Claraspital

    Basel, 4058, Switzerland

  • Clinexpert Kft.

    Budapest, 1033, Hungary

  • Clinic of the SRI of Invalid Rehab (EST Complex) of Pirogov Memorial NMU

    Vinnytsia, 21029, Ukraine

  • Clinica Gaias - Santiago

    Santiago de Compostela, La Coruña, 15702, Spain

  • Clinical Hospital Feofaniia of State Management of Affairs

    Kyiv, 03143, Ukraine

  • Clinical Research Of Brandon, LLC

    Brandon, Florida, 33511, United States

  • Clinnova Research Solutions

    Orange, California, 92868, United States

  • Concord Repatriation General Hospital

    Concord, New South Wales, 2139, Australia

  • Cook Children's Medical Center

    Fort Worth, Texas, 76104, United States

  • Coral Sea Clinical Research Institute

    North Mackay, Queensland, 4740, Australia

  • DCC "Alexandrovska", EOOD

    Sofia, 1431, Bulgaria

  • DSI Research LLC

    Springboro, Ohio, 45066, United States

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Dayanand Medical College and Hospital

    Ludhiana, Punjab, 141001, India

  • Debreceni Egyetem

    Debrecen, Hungary

  • Del Sol Research Management, LLC

    Tucson, Arizona, 85715, United States

  • Digestive Health Specialists of the Southeast

    Dothan, Alabama, 36305, United States

  • Digestive Research of Central Texas, LLC

    Waco, Texas, 76301, United States

  • Dnipro Division Medical Center Clinic of Family Medicine of LLC

    Dnipro, 49000, Ukraine

  • Dong-A University Hospital

    Busan, 49201, South Korea

  • ETG Zamosc

    Zamość, 22-400, Poland

  • ETZ Elisabeth

    Tilburg, 5022 GC, Netherlands

  • Eagle Clinical Research

    Chicago, Illinois, 60621, United States

  • Ege University Medical Faculty

    Izmir, 35100, Turkey (Türkiye)

  • Endoscopic Research, Inc.

    Orlando, Florida, 32803, United States

  • First Affiliated Hospital of Kunming Medical University

    Kunming, Yun'nan, 650032, China

  • Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico

    Milan, 20122, Italy

  • Fondazione IRCCS Policlinico San Matteo

    Pavia, 27100, Italy

  • Fondazione Poliambulanza Istituto Ospedaliero

    Brescia, 25124, Italy

  • Fortis Memorial Research Institute

    Gurgaon, Haryana, 122002, India

  • GI Alliance

    Sun City, Arizona, 85351, United States

  • GI Alliance

    Glenview, Illinois, 60026, United States

  • GI Alliance

    Gurnee, Illinois, 60031, United States

  • GI Alliance - Garland

    Garland, Texas, 75044, United States

  • GI Alliance - Southlake

    Austin, Texas, 76092, United States

  • GI Alliance - Webster

    Webster, Texas, 77598, United States

  • GI Alliance -Gurnee

    Mansfield, Texas, 76063, United States

  • Gachon University Gil Medical Center

    Incheon, 21565, South Korea

  • Gastro Care Institute

    Lancaster, California, 93534, United States

  • Gastro Health & Nutrition

    Katy, Texas, 78754, United States

  • Gastroenterologie Berlin Karlshorst

    Berlin, 10318, Germany

  • Gastroenterology Associates of Pensacola, PA

    Pensacola, Florida, 32503, United States

  • Gastroenterology Center of the MidSouth PC

    Germantown, Tennessee, 38138, United States

  • Gastroenterology and Internal Medicine Research Institute

    Edmonton, Alberta, T5R 1W2, Canada

  • Gazi University Medical Faculty

    Ankara, 06500, Turkey (Türkiye)

  • General Hospital of Athens "Evangelismos"

    Athens, 10676, Greece

  • General Hospital of Eastern Theater Command

    Nanjing, Jiangsu, 210002, China

  • General Hospital of Thessaloniki "Hippokration"

    Thessaloniki, 54642, Greece

  • HUB Erasme

    Brussels, 1070, Belgium

  • Hammersmith Hospital

    London, Greater London, W12 0HS, United Kingdom

  • Hepato-Gastroenterologie HK s.r.o.

    Hradec Králové, 50012, Czechia

  • Hopital Saint Eloi

    Montpellier, Herault, 34295, France

  • Hospital Privado Centro Medico de Cordoba S.A

    Córdoba, X5016KEH, Argentina

  • Hospital Universitari i Politecnic La Fe

    Valencia, 46026, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • Hospital da Luz

    Lisbon, 1500-650, Portugal

  • Hospital da Senhora da Oliveira Guimarães

    Guimarães, 4835-044, Portugal

  • Hospital de Braga

    Braga, 4710-243, Portugal

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Huddersfield Royal Infirmary

    Huddersfield, West Yorkshire, HD3 3EA, United Kingdom

  • Huzhou Central Hospital

    Huzhou, Zhejiang, 313099, China

  • Hôpital Bicêtre

    Le Kremlin-Bicêtre, Val De Marne, 94275, France

  • Hôpital Henri Mondor

    Créteil, Val De Marne, 94010, France

  • Hôpital Saint-Louis

    Paris, 75475, France

  • I.R.C.C.S Policlinico San Donato

    San Donato Milanese, Milano, 20097, Italy

  • IRCCS Ospedale Casa Sollievo della Sofferenza

    San Giovanni Rotondo, Foggia, 71013, Italy

  • Indiana University School of Medicine

    Indianapolis, Indiana, 46202, United States

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Inselspital - Universitaetsspital Bern

    Bern, 3010, Switzerland

  • Instituto de Investigaciones Clinicas Quilmes

    Quilmes, Buenos Aires, B1878GEG, Argentina

  • Intesto Gastroenterologische Praxis, Crohn-Colitis-Zentrum Bern

    Bern, 3012, Switzerland

  • Jiangxi Gannan Medical College Affiliated 1 st Hospital

    Ganzhou, Jiangxi, 341000, China

  • Jinan Central Hospital

    Jinan, Shandong, 250013, China

  • K.L.E. Society's Dr. Prabhakar Kore Hospital and Medical Research Centre

    Belagāve, Karnataka, 590010, India

  • KH der Barmherzigen Brüder St.Veit an der Glan

    Sankt Veit an der Glan, 9300, Austria

  • Kiepury Clinic MAŁGORZATA JARNOT SPECJALISTYCZNA PRAKTYKA GINEKOLOGICZNO-POŁOŻNICZA

    Sosnowiec, 41-200, Poland

  • King's College Hospital

    London, Greater London, SE5 9NU, United Kingdom

  • Kingsway Hospital

    Nagpur, Maharashtra, 440001, India

  • Kocaeli Universitesi Tip Fakultesi

    Kocaeli, 41380, Turkey (Türkiye)

  • Korea University Ansan Hospital

    Ansan-si, Gyeonggi-do, 15355, South Korea

  • Kyung Hee University Hospital

    Seoul, 02447, South Korea

  • Kyungpook National University Hospital

    Daegu, 41944, South Korea

  • LKH - Universitaetsklinikum Graz

    Graz, 8036, Austria

  • LKH - Universitätsklinikum der PMU Salzburg

    Salzburg, 5020, Austria

  • LLC Medical Center The Clinic of Hospodarskyy

    Ternopil, 46002, Ukraine

  • LMU - Campus Grosshadern

    Munich, Bavaria, 81337, Germany

  • Lakeview Clinical Research

    Guntersville, Alabama, 35976, United States

  • Liaocheng People's Hospital

    Liaocheng, Shandong, 252000, China

  • Limited Liability Company Medical Center Health Clinic, Medical Clinical Research Center

    Vinnytsia, 21009, Ukraine

  • Liuzhou People's Hospital

    Liuzhou, Guangxi Zhuang, 545006, China

  • Liverpool Hospital

    Liverpool, New South Wales, 2170, Australia

  • Lubbock Digestive Disease Associates

    Lubbock, Texas, 79410, United States

  • Lucida Clinical Trials LLC

    New Bedford, Massachusetts, 02740, United States

  • M. S. Ramaiah Medical College and Hospital

    Bangalore, Karnataka, 560054, India

  • Mater Misericordiae Ltd

    South Brisbane, Queensland, 4101, Australia

  • McGill University Health Centre- Montreal General Hospital

    Montreal, Quebec, H3G 1A4, Canada

  • Medical Center of Limited Liability Company Medical Center Concilium Medical

    Kyiv, 04050, Ukraine

  • Medical Center of Limited Liability Company Saliutas

    Lviv, 79005, Ukraine

  • Medical Professional Clinical Research Center

    Miami, Florida, 33165, United States

  • Medical center Medconsult Pleven OOD

    Pleven, 5800, Bulgaria

  • Medizinische Hochschule Hannover

    Hanover, Lower Saxony, 30625, Germany

  • Medizinische Universität Innsbruck

    Innsbruck, 6020, Austria

  • Mersin University Medical Faculty

    Mersin, 33343, Turkey (Türkiye)

  • Midas Multispeciality Hospital Pvt Ltd

    Nagpur, Maharashtra, 440010, India

  • NSZOZ Termedica - Centrum Badan Klinicznych

    Poznan, 60-681, Poland

  • NZOZ Centrum Medyczne ProMiMed

    Krakow, 31-637, Poland

  • NZOZ VIVAMED Jadwiga Miecz

    Warsaw, 03-580, Poland

  • Nanfang Hospital of Southern Medical University

    Guangzhou, Guangdong, 510515, China

  • Nature Coast Clinical Research - Inverness

    Inverness, Florida, 34452, United States

  • Navneet Memorial Hospital 'Sushrusha'

    Ahmedabad, Gujarat, 380009, India

  • Nemocnice Slany

    Slaný, 27401, Czechia

  • Nil Ratan Sircar Medical College

    Kolkata, West Bengal, 700014, India

  • Novel Research LLC

    Bellaire, Texas, 77401, United States

  • One Health Research Clinic Atlanta, LLC

    Norcross, Georgia, 30093, United States

  • Orlando Health-Orlando Regional Medical Center

    Orlando, Florida, 32806, United States

  • Ospedale Sacro Cuore Don Calabria

    Negrar, Italy

  • Ospedale San Raffaele

    Milan, 20132, Italy

  • Pannonia Maganorvosi Centrum

    Budapest, 1136, Hungary

  • Peak Gastroenterology Associates

    Colorado Springs, Colorado, 80907, United States

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100191, China

  • PlanetMed sp. z o.o.

    Wroclaw, 52-210, Poland

  • Praxis fuer Gasroenterologie Prof. Dr. med Robert Ehehalt

    Heidelberg, Baden-Wurttemberg, 69121, Germany

  • PreventaMed s.r.o.

    Olomouc, 77200, Czechia

  • Przychodnia Specjalistyczna Insula

    Bełchatów, 97-400, Poland

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

  • RCNE Chernivtsi Regional Clinical Hospital Gastroenterology Subdivision Bukovinian SMU

    Chernivtsi, 58001, Ukraine

  • Renji Hospital Shanghai Jiaotong University School of Medicine - West Branch

    Shanghai, Shanghai Municipality, 200127, China

  • Renmin Hospital, Wuhan University

    Wuhan, Hubei, 430060, China

  • Rochester Clinical Research

    Rochester, New York, 14609, United States

  • Royal London Hospital

    London, Greater London, E1 1FR, United Kingdom

  • Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • Royal Perth Hospital

    Perth, Western Australia, 6000, Australia

  • Ruby Hall Clinic

    Pune, Maharashtra, 411001, India

  • Ruijin Hospital of Shanghai Jiaotong University School of Medicine

    Shanghai, Shanghai Municipality, 200025, China

  • S. R. Kalla Memorial Gastro & General Hospital

    Jaipur, Rajasthan, 302001, India

  • SOLUMED Centrum Medyczne

    Poznan, 60-529, Poland

  • STAT Research S.A.

    Ciudad Autonoma Buenos Aires, C1013AAB, Argentina

  • Sahyadri Specialty Hospital

    Pune, Maharashtra, 411028, India

  • Samodzielny Publiczny Zakład Opieki Zdrowotnej w Lecznej

    Łęczna, 21-010, Poland

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Scott Shulman Medicine Professional Corporation

    North Bay, Ontario, P1B 2H3, Canada

  • Semmelweis Egyetem

    Budapest, 1082, Hungary

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Shengjing Hospital of China Medical University

    Shenyang, Liaoning, 110022, China

  • Shree Giriraj Multispeciality Hospital

    Rajkot, Gujarat, 360005, India

  • Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310018, China

  • St Mark's the National Bowel Hospital

    London, Greater London, NW10 7NS, United Kingdom

  • St Vincent's Hospital Melbourne

    Fitzroy, Victoria, 3065, Australia

  • Staedisches Klinikum Brandenburg

    Brandenburg an der Havel, Brandenburg, 14770, Germany

  • SurGal Clinic s.r.o.

    Brno, 60200, Czechia

  • Szpital Zakonu Bonifratow Sp. z o.o.

    Katowice, 40-211, Poland

  • Taian City Central Hospital

    Tai’an, Shandong, 271000, China

  • Texas Digestive Disease Consultants

    Cedar Park, Texas, 78613, United States

  • The 2nd Xiangya Hospital of Central South University

    Changsha, Hu'nan, 410011, China

  • The 900th Hospital of The Chinese People's Liberation Army Joint Logistics Support Force

    Fuzhou, Fujian, 350025, China

  • The Affiliated Hospital of Qingdao University

    Qingdao, Shandong, 266003, China

  • The Affiliated Hospital of Southwest Medical University

    Luzhou, Sichuan, 646099, China

  • The Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • The Catholic University of Korea, Daejeon St. Mary's Hospital

    Daejeon, 34943, South Korea

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    Seoul, 06591, South Korea

  • The Catholic University of Korea, St. Vincent's Hospital

    Suwon, Gyeonggi-do, 16247, South Korea

  • The First Affiliated Hospital of Anhui Medical University

    Hefei, Anhui, 230022, China

  • The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, 350005, China

  • The First Affiliated Hospital of Henan University of Science and Technology

    Luoyang, Henan, 471003, China

  • The First Affiliated Hospital of Nanyang Medical College

    Nanyang, Henan, 473000, China

  • The First Affiliated Hospital of Sun Yat-sen University

    Yuexiu, Guangdong, 510080, China

  • The First Affiliated Hospital of University of South China

    Hengyang, Hu'nan, 421001, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450000, China

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310003, China

  • The First People's Hospital of Foshan

    Foshan, Guangdong, 528000, China

  • The Second Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The Sixth Affiliated Hospital of Sun Yat-sen University

    Guangzhou, Guangdong, 510655, China

  • The Ulster Hospital

    Belfast, BT16 1RH, United Kingdom

  • Theia Clinical Research Centers, LLC

    Temple Terrace, Florida, 33617, United States

  • Tianjin Union Medical Center

    Tianjin, Tianjin Municipality, 300121, China

  • Twoja Przychodnia Opolskie Centrum Medyczne

    Opole, 45-819, Poland

  • Twoja Przychodnia PCM

    Poznan, 61-293, Poland

  • Twoja Przychodnia-Szczecinskie Centrum Medyczne Sp. z o. o.

    Szczecin, 71-434, Poland

  • UMHAT 'Tsaritsa Yoanna - ISUL', EAD

    Sofia, 1527, Bulgaria

  • UMHAT Prof. Dr. Stoyan Kirkovich AD

    Stara Zagora, 6000, Bulgaria

  • UZ Leuven

    Leuven, 3000, Belgium

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Unity Hospital ICU and Trauma

    Surat, Gujarat, 395010, India

  • Universitaetsklinikum Erlangen

    Erlangen, Bavaria, 91054, Germany

  • Universitaetsklinikum Essen

    Essen, North Rhine-Westphalia, 45147, Germany

  • Universitaetsklinikum Frankfurt Goethe-Universitaet

    Frankfurt am Main, Hesse, 60590, Germany

  • Universitaetsklinikum Heidelberg

    Heidelberg, Baden-Wurttemberg, 69120, Germany

  • Universitaetsklinikum Schleswig-Holstein - Campus Kiel

    Kiel, Schleswig-Holstein, 24105, Germany

  • Universitaetsspital Zuerich

    Zurich, 8091, Switzerland

  • University of Kansas Medical Center Research Institute, Inc.

    Kansas City, Kansas, 66160, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Varlik Mah. Kazim Karabekir Cad.

    Muratpaşa, 07100, Turkey (Türkiye)

  • Vojenska nemocnice Brno

    Brno, Czechia

  • West China Hospital, Sichuan University

    Sichuan, China

  • Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200082, China

  • Yeovil District Hospital

    Yeovil, Somerset, BA21 4AT, United Kingdom

  • Yeungnam University Hospital

    Daegu, Gyeongsangbuk-do, 42415, South Korea

  • Yijishan Hospital of Wannan Medical College

    Wuhu, Anhui, 241001, China

  • Yonsei University Wonju Severance Christian Hospital

    Wŏnju, Gangwon-do, 26426, South Korea

  • Zhongda Hospital Southeast University

    Nanjing, Jiangsu, 210009, China

  • Zhongshan Hospital Xiamen University

    Xiamen, Fujian, 361004, China

  • Zuyderland Medisch Centrum - Sittard-Geleen

    Sittard, 6162 BG, Netherlands

  • ongji Hospital, Tongji Medical College, Huazhong University of Science & Technology

    Wuhan, Hubei, 430030, China

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