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New immunotherapy combo tested for Hard-to-Treat cancers

NCT ID NCT02988960

First seen Jan 10, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This early-stage study tests two experimental immunotherapy drugs, ABBV-927 and ABBV-181, in people with advanced solid tumors that have not responded to standard treatments. The main goals are to find the safest dose and understand how the drugs move through the body. About 163 participants will receive the drugs alone or together, and researchers will monitor side effects and any tumor shrinkage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Austin Health /ID# 171189

    Heidelberg, Victoria, 3084, Australia

  • Carolina BioOncology Institute /ID# 155265

    Huntersville, North Carolina, 28078, United States

  • Centre Leon Berard /ID# 162663

    Lyon, Rhone, 69373, France

  • Duplicate_Institut Regional du Cancer /ID# 163609

    Montpellier, Herault, 34298, France

  • Hospital Universitario Fundacion Jimenez Diaz /ID# 200128

    Madrid, 28040, Spain

  • Hospital Universitario HM Sanchinarro /ID# 200127

    Madrid, 28050, Spain

  • Hospital Universitario Puerta de Hierro - Majadahonda /ID# 200129

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario y Politecnico La Fe /ID# 200975

    Valencia, 46026, Spain

  • Institut Bergonie /ID# 162665

    Bordeaux, Gironde, 33000, France

  • Institut Gustave Roussy /ID# 162666

    Villejuif, Val-de-Marne, 94805, France

  • Massachusetts General Hospital /ID# 155267

    Boston, Massachusetts, 02114, United States

  • National Cancer Center Hospital /ID# 217758

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East /ID# 216870

    Kashiwa-shi, Chiba, 277-8577, Japan

  • Peninsula Oncology Centre /ID# 164372

    Frankston, Victoria, 3199, Australia

  • Seoul National University Hospital /ID# 166291

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Tennessee Oncology-Nashville Centennial /ID# 158654

    Nashville, Tennessee, 37203-1632, United States

  • The Angeles Clinic and Researc /ID# 156324

    Los Angeles, California, 90025, United States

  • The University of Chicago Medical Center /ID# 155264

    Chicago, Illinois, 60637-1443, United States

  • University Health Network_Princess Margaret Cancer Centre /ID# 200819

    Toronto, Ontario, M5G 2M9, Canada

  • University of Texas MD Anderson Cancer Center /ID# 155263

    Houston, Texas, 77030, United States

  • Virginia Cancer Specialists - Fairfax /ID# 155266

    Fairfax, Virginia, 22031, United States

  • Yonsei University Health System Severance Hospital /ID# 166292

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.