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New hope for Hard-to-Treat myeloma: first human trial of ABBV-438 begins

NCT ID NCT07409246

First seen Feb 20, 2026 · Last updated May 22, 2026 · Updated 15 times

Summary

This early-stage study tests a new drug called ABBV-438 in about 127 adults with multiple myeloma that has returned or not responded to prior treatments. The main goals are to check the drug's safety, find the best dose, and see if it helps shrink the cancer. Participants receive the drug through an IV, and the study lasts about 5.8 years total.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City Of Hope - Atlanta. /ID# 280294

    RECRUITING

    Newnan, Georgia, 30265, United States

  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 279067

    RECRUITING

    Irvine, California, 92618, United States

  • City of Hope National Medical Center /ID# 280273

    RECRUITING

    Duarte, California, 91010, United States

  • Colorado Blood Cancer Institute /ID# 280275

    RECRUITING

    Denver, Colorado, 80218, United States

  • Hadassah Medical Center-Hebrew University /ID# 278865

    RECRUITING

    Jerusalem, 91120, Israel

  • START Midwest /ID# 279035

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • Tel Aviv Sourasky Medical Center /ID# 279066

    RECRUITING

    Tel Aviv, Tel Aviv, 6423906, Israel

  • The Cancer Institute Hospital Of JFCR /ID# 279069

    RECRUITING

    Koto-ku, Tokyo, 135-8550, Japan

  • The Chaim Sheba Medical Center /ID# 279065

    RECRUITING

    Ramat Gan, Tel Aviv, 5265601, Israel

Conditions

Explore the condition pages connected to this study.