Can 3D printing match milled resin for durable Back-Tooth fillings?
NCT ID NCT07811167
First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time
Summary
Researchers at the University of Valencia are comparing two ways to make indirect resin restorations for back teeth: 3D printing and CAD/CAM milling. Seventy adults who need an onlay or overlay on a premolar or molar will be randomly assigned to receive one type or the other. A blinded assessor will check how well each restoration holds up, how much it wears, and how its color changes over 36 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 3D-printed resin onlay/overlay restorations (saremco print CrownTec) versus CAD/CAM-milled resin restorations (Brilliant Crios)
- What this could lead to
- If 3D-printed resin restorations hold up as well as milled ones, dentists could make durable custom fillings faster and possibly at lower cost.
- What could go wrong
- This is a single-center study of 70 patients over three years, so results may not apply to all dental practices. Printed resins may wear faster or fail sooner than milled blocks, and longer-term durability beyond three years remains unknown.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Adult patients (≥18 years) attending the University Dental Clinic (Universitat de València) in need of a posterior indirect partial restoration (onlay/overlay) * Permanent posterior tooth (premolar or molar) presenting extensive coronal destruction (caries, fracture, or failed previous restoration) requiring indirect restoration, with at least one weakened or missing cusp * Sufficient remaining tooth structure to allow adequate adhesive isolation (rubber dam) and adhesive cementation * Tooth classified as either vital (Stratum 1) or endodontically treated with an adequate, asymptomatic root canal filling and no radiographic signs of periapical pathology (Stratum 2) * Natural antagonist dentition * Favorable occlusal relationship * Healthy periodontal status or adequately controlled periodontal disease (probing depth ≤ 3 mm, no active clinical attachment loss) * Willingness and ability to attend all scheduled follow-up visits over the 24-month study period * Signed informed consent Exclusion Criteria: * • Known allergy or hypersensitivity to methacrylate-based materials, Bis-EMA, or any component of the restorative materials used (per manufacturer contraindications for saremco print CrownTec® and Brilliant Crios) * Parafunctional habits (bruxism, clenching, or foreign object chewing) without adequate occlusal protection * Active or untreated periodontal disease * Poor oral hygiene or inability to maintain adequate plaque control * Temporomandibular joint disorders * Tooth requiring full-coverage restoration (crown) rather than a partial indirect restoration * Endodontically treated tooth with inadequate root canal filling, periapical pathology, or insufficient remaining coronal structure to support the restoration without additional foundation (e.g., post/core) beyond the study protocol * Pregnant or breastfeeding patients * Uncontrolled systemic disease that could compromise treatment outcome or follow-up compliance * Active substance abuse * Participation in another interventional clinical trial that could interfere with study outcomes * Inability to provide informed consent
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As listed by the trial registrant
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How to take part
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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