Radiation-Free lung imaging could replace CT scans?
NCT ID NCT07756086
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This study tests whether a noninvasive, radiation-free imaging method called 3D electrical impedance tomography (3D-EIT) can accurately measure how air distributes in the lungs during breathing. Researchers will compare it to 4D computed tomography (4D-CT), which provides detailed images but uses radiation. About 50 adults, including healthy volunteers and ICU patients, will undergo both scans simultaneously. If 3D-EIT matches CT's accuracy, it could offer a safer, continuous way to monitor lung ventilation in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Three-Dimensional Electrical Impedance Tomography (3D-EIT) device
- What this could lead to
- If 3D-EIT proves accurate, it could become a noninvasive, radiation-free way to monitor lung ventilation in real time, especially for critically ill patients.
- What could go wrong
- This is a small observational study, and 3D-EIT may not match CT's precision. Its results are for research only and won't guide treatment decisions yet.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will include adults aged 18 years or older recruited at the Department of Critical Care Medicine, Zhongshan Hospital, Fudan University. Participants will consist of healthy volunteers and intensive care unit patients for whom CT imaging is considered necessary based on the treating physician's clinical judgment. Eligible participants must be able to undergo simultaneous 4D-CT and 3D-EIT monitoring. This is a prospective, observational, single-center study. Participation will not alter the participant's routine clinical management, and the research-derived three-dimensional EIT reconstruction results will not be used directly to make clinical treatment decisions.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older. * Healthy volunteers or patients in the intensive care unit for whom CT imaging is considered necessary based on the treating physician's clinical judgment. * Able to cooperate with or undergo simultaneous 4D-CT and 3D-EIT monitoring. * Able to provide written informed consent personally or through a legally authorized representative, as applicable. Exclusion Criteria: * Unable to tolerate or having a contraindication to 4D-CT examination, including pregnancy or severe respiratory distress. * Extensive chest skin injury or infection, or any condition preventing placement of the EIT electrode belt. * Body size or chest deformity that may substantially limit the quality of EIT or CT data, including chest circumference outside the compatible range of the EIT device. * Presence of an implanted electronic device that may interfere with EIT signals, such as a cardiac pacemaker. * Unable to complete simultaneous 4D-CT and 3D-EIT monitoring because of significant motion, persistent coughing, poor cooperation, or other technical or clinical reasons. * Any other condition that, in the investigator's judgment, makes the individual unsuitable for participation in the study.
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As listed by the trial registrant
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How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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