Experimental cancer combo tested in tiny, terminated trial

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18 years or older. 2. Histologically or cytological documented solid tumor. 3. Available tumor biopsy (most recent) for DRP® analysis. 4. Measurable disease by CT scan or MRI if possible. 5. Performance status of ECOG ≤ 1. 6. Recovered to Grade \<1 or baseline from prior surgery or from acute toxicities of prior radiotherapy, or from treatment with cytotoxic, hormonal or biologic agents. 7. ≥ 2 weeks must have elapsed since any prior surgery or therapy with G-CSF and GM-CSF. 8. Patients with intracranial disease must be on stable or decreased level of steroid therapy (e.g. dexamethasone) for at least 7 days prior to baseline MRI. Non-enzymatic inducing anti-epileptic drugs are allowed. 9. Adequate conditions as evidenced by the following clinical laboratory values: 1. Absolute neutrophils count (ANC) ≥ 1500/mm3 (1.5 x 10³/mL) 2. Hemoglobin \> 10.0 g/dL 3. Platelets ≥ 100,000/mm3 (≥ 100 x 10⁹/L) 4. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 3 x ULN or ≤5x ULN in presence of liver metastases 5. Serum bilirubin ≤ 1.5 ULN 6. Alkaline phosphatase ≤ 2.5 x ULN 7. Creatinine ≤ 1.5 ULN 8. Blood urea nitrogen (BUN) ≤2X ULN. 10. Life expectancy equal or longer than 3 months. 11. The subject is willing to provide written informed consent to participate in the study after reading the informed consent form and the information provided and has had the opportunity to discuss the study with the investigator or designee. 12. The subject is able to communicate satisfactorily with the investigator and to participate in, and comply with, the requirements of the study. 13. The subject is able to understand the nature of the study and any potential hazards associated with participating in it. 14. Negative pregnancy test for female subjects of childbearing potential. Women of childbearing potential (WOCBP) and Women of non-childbearing potential are eligible to participate. Both women of childbearing potential and women of non-childbearing potential should use an approved method of birth control and agree to continue to use this method for the duration of the study (and for 90 days after taking the last dose of study drug). Acceptable methods of contraception include abstinence, female subject/partner's use of hormonal contraceptive (oral, implanted, or injected) in conjunction with a barrier method (WOCBP only) (e.g., diaphragm, cervical cap, male condom, and female condom and spermicidal foam, sponges, and film), female subject/partner's use of an intrauterine device (IUD), or if the female subject/partner is surgically sterile for at least three months before screening or 2 years post-menopausal at time of screening. All male subjects/partners must agree to consistently and correctly use a condom for the duration of the study and for 90 days after taking the study drug. In addition, subjects may not donate sperm for the duration of the study and for 90 days after taking study drug. \- Exclusion Criteria: 1. Concurrent chemotherapy, radiotherapy, hormonal therapy, or other investigational drug except non-disease related conditions (e.g. insulin for diabetes) during study period. 2. Other malignancy with exception of curative treated non-melanoma skin cancer or cervical carcinoma in situ within 5 years prior to entering the study. 3. Any active infection requiring parenteral or oral antibiotic treatment. 4. History of coagulation or bleeding disorder or subject currently on therapeutic anticoagulant medication. Note: Prophylactic doses of heparin or low molecular weight heparin are allowed. 5. Known HIV positivity. 6. Known active hepatitis B or C. 7. Clinically significant (i.e. active) cardiovascular disease: 1. Stroke within ≤ 6 months prior to day 1 2. Transient ischemic attack (TIA) within ≤ 6 months prior to day 1 3. Myocardial infarction within ≤ 6 months prior to day 1 4. Unstable angina 5. New York Heart Association (NYHA) Class II or greater congestive heart failure (CHF) 6. Serious cardiac arrhythmia requiring medication. 8. Other medications or conditions, including surgery, that in the Investigator's opinion would contraindicate study participation for safety reasons or interfere with the interpretation of study results. 9. Inability to take oral medication, or malabsorption syndrome or any other uncontrolled gastrointestinal condition (e.g., nausea, diarrhea, or vomiting) that might impair the bioavailability of 2X-121 and dovitinib. 10. Requiring immediate palliative treatment of any kind including surgery and/or radiotherapy. 11. Female patients who are pregnant or breast-feeding (pregnancy test with a positive result before study entry). \-