Therapeutic Advances In Childhood Leukemia Consortium
Clinical trials sponsored by Therapeutic Advances In Childhood Leukemia Consortium, explained in plain language.
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New drug combo aims to prime leukemia cells for destruction in tough childhood cancers
Disease control CompletedThis early-phase study tested whether using two drugs (decitabine and vorinostat) to 'reprogram' leukemia cells before standard chemotherapy is safe and could improve outcomes. It involved 37 children and young adults (ages 1-25) whose AML had returned or did not respond to prior…
Phase: PHASE1 • Sponsor: Therapeutic Advances in Childhood Leukemia Consortium • Aim: Disease control
Last updated Apr 04, 2026 05:05 UTC
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New hope for kids battling Leukemia's return
Disease control CompletedThis study tested the safety of a modified chemotherapy regimen for children and young adults whose acute lymphoblastic leukemia (ALL) had returned. It replaced one standard drug with a special, longer-acting version (Marqibo®) within a known treatment combination. The main goal …
Phase: PHASE1 • Sponsor: Therapeutic Advances in Childhood Leukemia Consortium • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC