Pirogov Russian National Research Medical University

This early-stage trial tests an experimental drug called ASO-GNAO1 (Tianasen) in 5 children aged 1-14 with a specific GNAO1 gene mutation that causes severe epilepsy and uncontrolled movements. The drug is given via spinal injections over 12 months to see if it can reduce seizure…

This study compares two different laser wavelengths (1940 nm and 1470 nm) for treating varicose veins. The goal is to see which one better prevents vein reflux and reduces pain after surgery. About 400 adults with varicose veins will take part to find the safest and most effectiv…

This study looks at 200 people with high-blood-pressure-related brain bleeding to find the best time to start blood thinners (heparin) to prevent dangerous clots in the legs or lungs. Participants get heparin either within 2 days (but not before 12 hours) or starting on day 3 aft…

This study is creating a tool to estimate a person's 'biological age'—how old their body really is—rather than just counting birthdays. Researchers will collect health, lifestyle, and lab data from 3,500 volunteers across Russia. The goal is to better understand aging and help pr…

This study checks if a tool called the Caprini score can accurately predict blood clots in people having varicose vein surgery. Researchers will follow 3,000 adults for four weeks after surgery to see who develops clots. The goal is to identify high-risk patients who would benefi…

This study looks at 100 people who recently had a stroke and need surgery to open a blocked neck artery. Half will get numbing medicine only in the neck (regional anesthesia), and the other half will be fully asleep (general anesthesia). The goal is to see which method leads to f…