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This study tests a new oral polio vaccine (nOPV3) in healthy young children, infants, and newborns in Panama. The goal is to see if it is safe and triggers a strong immune response compared to the current vaccine. About 1,500 participants will receive either the new or standard v…

This study tests the R21/Matrix-M malaria vaccine in about 964 African infants to find the best timing for shots. Researchers compare a standard schedule (6, 10, 14 weeks) with two relaxed schedules (2, 4, 6 months and 3, 6, 9 months). The goal is to see which schedule works best…

This study tests whether giving two new polio vaccines together is safe and works as well as giving them separately in healthy infants. Around 675 babies in Panama will receive either the combined vaccines or single vaccines. The goal is to find a simpler way to protect more chil…

This study tests a new oral polio vaccine (nOPV1) in over 2,200 healthy children, infants, and newborns in Bangladesh. The goal is to see if it is safe and triggers a strong immune response compared to the current vaccine. Researchers will monitor side effects and measure antibod…