Janssen Research & Development, Llc
Clinical trials sponsored by Janssen Research & Development, Llc, explained in plain language.
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Lupus kidney drug trial pulled before it began
Disease control TerminatedThis study aimed to test whether nipocalimab, an experimental drug, could help people with active lupus nephritis (kidney inflammation caused by lupus). The trial was planned for adults with confirmed kidney disease and high protein in their urine. However, the study was withdraw…
Phase: PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New CAR-T therapy shows promise in battle against Hard-to-Treat multiple myeloma
Disease control OngoingThis study tests a new treatment called cilta-cel, which uses a patient's own immune cells to fight multiple myeloma, against two standard drug combinations. The trial involves 419 adults whose cancer has returned and no longer responds to the drug lenalidomide. The main goal is …
Phase: PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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Lung cancer patients may get safer infusions with simple Pre-Medications
Prevention OngoingThis study tests whether giving dexamethasone, montelukast, or methotrexate before an amivantamab infusion can reduce or prevent infusion-related reactions in people with advanced non-small cell lung cancer. The trial enrolled 68 participants who had previously taken osimertinib.…
Phase: PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Prevention
Last updated May 06, 2026 16:02 UTC
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Scientists launch global vision registry to track rare eye diseases
Knowledge-focused OngoingThis study is a global registry that follows about 889 people with inherited retinal diseases (IRDs) to learn how their vision changes over time. Participants must have a genetic variant linked to certain IRDs. The goal is to better understand the natural course of these diseases…
Sponsor: Janssen Research & Development, LLC • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC