Huyabio International, Llc.

This Phase 3 trial tests whether adding an experimental drug, HBI-8000, to the standard immunotherapy nivolumab helps people with advanced melanoma that cannot be surgically removed or has spread. About 450 adults with melanoma not previously treated with PD-1/PD-L1 inhibitors ar…

This study tests a single 30-minute IV infusion of HBI 3000 in 150 adults with atrial fibrillation that started within the last 3 days. The goal is to safely convert the heart back to normal rhythm. The trial first finds the best dose, then compares it to a placebo in a blinded f…

This early-phase trial tests an experimental oral drug called HBI-2376 in about 42 people with advanced solid tumors (lung, colon, pancreatic, and others) that have specific KRAS or EGFR gene mutations and have stopped responding to standard treatments. The main goals are to find…

This early-stage study tests a new drug, HBI-2438, in people with advanced cancers (like lung, colon, or pancreatic) that have a specific genetic change called KRAS G12C. The main goals are to find the safest dose and understand how the drug works in the body. About 44 adults who…