Hutchmed

This study tests an experimental drug, HMPL-453, in people with advanced bile duct cancer that has a specific change in the FGFR2 gene. The goal is to see if the drug can shrink tumors or stop them from growing. Participants take the drug as a pill for 14 days, then a 7-day break…

This study tests a new drug called HMPL-A580 in adults with advanced or metastatic solid tumors that cannot be removed by surgery. The main goals are to find a safe dose and see if the drug can shrink tumors. About 186 participants will take part in this early-phase trial.

This study tests whether adding two drugs (surufatinib and camrelizumab) to standard chemotherapy helps people with metastatic pancreatic cancer live longer. About 502 adults aged 18-75 who have not had prior treatment for their advanced cancer will take part. The goal is to see …

This study tests a new drug called HMPL-A251 in adults with advanced or metastatic solid tumors that have a protein called HER2. The main goals are to find a safe dose and see if the drug can shrink tumors. About 147 participants will receive the drug, and researchers will monito…

This study tests whether adding the experimental drug HMPL-760 to standard chemotherapy (R-GemOx) can help control diffuse large B-cell lymphoma that has come back or stopped responding to treatment. About 240 adults will take part. The goal is to see if the combination slows can…

This early-stage study tests an experimental pill called HMPL-506 for people with certain blood cancers (like AML and ALL) that have come back or not responded to treatment. The main goals are to check the drug's safety and find the right dose. About 132 adults will take part in …