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D. E. Shaw Research, Llc

Clinical trials sponsored by D. E. Shaw Research, Llc, explained in plain language.

Not yet recruiting 1

Can a pill target a Hard-to-Treat colorectal cancer?

Disease control Not yet recruiting

This trial tests an experimental oral drug called DES-1357 in adults with metastatic colorectal cancer that has specific genetic features (dMMR or MSI-H). The study runs in three parts: first, to find a safe dose; second, to check tolerability and early signs of tumor shrinkage; …

Phase 1/2 • Sponsor: D. E. Shaw Research, LLC • Aim: Disease control

Last updated Sep 10, 2026 00:00 UTC