Cytokinetics

This study is testing whether a new drug called omecamtiv mecarbil can help people with severe heart failure live longer and avoid hospital visits, transplants, or strokes. About 1,800 participants will receive either the drug or a placebo pill for up to three years while continu…

This study is testing whether a drug called aficamten is safe and effective for children and teenagers with a genetic condition that causes the heart muscle to thicken, making it harder to pump blood. Participants will take the drug or a placebo for 12 weeks, followed by a longer…

This study is testing an investigational drug called CK-4021586 in adults with a specific type of heart failure where the heart pumps normally but still causes symptoms like shortness of fatigue. The main goals are to find a safe and effective dose and see how the body processes …