Clinical Hub For Interventional Research (choir)
Clinical trials sponsored by Clinical Hub For Interventional Research (choir), explained in plain language.
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Experimental combo aims to improve treatment for blood cancer patients
Disease control Recruiting nowThis early-phase study tests whether adding an experimental drug (defactinib) to an approved oral treatment (decitabine/cedazuridine) is safe and tolerable for people with high-risk myelodysplastic syndromes, certain acute myeloid leukemias, and chronic myelomonocytic leukemia. A…
Phase: PHASE1 • Sponsor: Clinical Hub for Interventional Research (CHOIR) • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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New study monitors hidden blood condition to predict future disease
Knowledge-focused Recruiting nowThis study follows 100 people aged 55 and older who have clonal hematopoiesis (CH) or possible CH, a condition where blood cells carry certain genetic changes. Researchers will monitor participants' health, check for risks of heart disease and blood cancers, and provide personali…
Sponsor: Clinical Hub for Interventional Research (CHOIR) • Aim: Knowledge-focused
Last updated May 26, 2026 12:02 UTC
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Mice with human AML cells could speed up cancer drug discovery
Knowledge-focused Recruiting nowThis study aims to develop a faster way to test new drug combinations for acute myeloid leukemia (AML). Researchers will take blood and bone marrow samples from 25 AML patients and grow their cancer cells in special mice. They will then test how well standard treatments work in t…
Sponsor: Clinical Hub for Interventional Research (CHOIR) • Aim: Knowledge-focused
Last updated May 22, 2026 14:05 UTC