Aptabio Therapeutics, Inc.

This early-stage study tests a new drug called APX-343A, given alone or with an immunotherapy (pembrolizumab), in people with advanced solid tumors that have not responded to other treatments. The main goals are to check safety, find the best dose, and see if the drug can shrink …

This study tests whether a new drug called APX-115 can prevent kidney injury caused by contrast dye used during heart procedures. About 280 adults with heart disease will receive either the drug or a placebo before their procedure. The goal is to see if the drug reduces kidney da…

This early-stage study tests the safety of an experimental oral drug called ABF-101 in healthy adults and people with age-related macular degeneration (AMD). The goal is to see if the drug is safe and how the body processes it. About 68 participants will take single or multiple d…