Transfemoral amputation
Clinical trials for Transfemoral amputation explained in plain language.
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New adjustable socket could help veterans walk more comfortably
Symptom relief Recruiting nowThis study compares a new adjustable prosthetic socket to a standard rigid socket in 40 veterans with leg amputations. Participants will walk on a treadmill at different speeds while researchers measure how evenly they walk and how comfortable the socket feels. The goal is to fin…
Matched conditions: TRANSFEMORAL AMPUTATION
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Bionic knee study aims to make walking less tiring for amputees
Symptom relief Recruiting nowThis study tests whether a powered, computer-controlled prosthetic knee helps people with above-knee amputations walk more efficiently than their usual prosthesis. Researchers will measure oxygen use during walking on flat and sloped surfaces, along with balance confidence and ef…
Matched conditions: TRANSFEMORAL AMPUTATION
Sponsor: Loma Linda University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Power knee promises smoother steps for amputees
Symptom relief Recruiting nowThis study compares a powered prosthetic knee (Ossur Power Knee) to a standard microprocessor knee in 20 people with above-knee amputations. Participants will use each knee for a month, then researchers measure walking speed, energy use, and sit-to-stand movements. The goal is to…
Matched conditions: TRANSFEMORAL AMPUTATION
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 26, 2026 15:21 UTC
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How does losing more of a leg change strength and balance? researchers measure the difference
Knowledge-focused Recruiting nowResearchers are studying how muscle strength, balance, and walking ability differ in people with an above-knee amputation. The study measures strength at the hip, knee, and ankle of the intact leg, tests balance on a force platform, and records how far participants walk in six mi…
Matched conditions: TRANSFEMORAL AMPUTATION
Sponsor: Ceren Kuzu • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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AI learns to tune robotic legs in half the time
Knowledge-focused Recruiting nowThis study tests a new AI system that helps doctors and prosthetists quickly tune robotic prosthetic legs for people with above-knee amputations. 24 participants will compare AI-guided tuning against manual tuning to see which is faster and leads to better walking. The goal is to…
Matched conditions: TRANSFEMORAL AMPUTATION
Phase 1 • Sponsor: North Carolina State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Mind-Controlled bionic leg helps amputees walk naturally
Knowledge-focused Recruiting nowThis study tests a bionic leg that uses muscle signals from the user's residual limb to control the knee and ankle. Ten people with above-knee amputations will compare walking with this smart prosthesis versus their regular one. The goal is to see if the bionic leg feels more lik…
Matched conditions: TRANSFEMORAL AMPUTATION
Sponsor: Massachusetts Institute of Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC