SYSTEMIC MASTOCYTOSIS
Clinical trials for SYSTEMIC MASTOCYTOSIS explained in plain language.
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Experimental antibody shows promise in tough blood cancers
Disease control CompletedThis early-stage trial tested the safety of flotetuzumab, an antibody that targets cancer cells, in 13 people with advanced blood cancers that had returned or stopped responding to treatment. The goal was to find the best dose and understand side effects. While not a cure, it aim…
Matched conditions: SYSTEMIC MASTOCYTOSIS
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 01, 2026 15:41 UTC
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New hope for rare bone disease: drug may strengthen fragile bones
Disease control CompletedThis study tested whether a drug called denosumab can improve bone density in adults with osteoporosis caused by systemic mastocytosis, a rare disease where too many mast cells weaken bones. Twenty-four participants received either denosumab or a placebo every 6 months for 3 year…
Matched conditions: SYSTEMIC MASTOCYTOSIS
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 01, 2026 15:40 UTC