SLEEP WAKE DISORDERS

This study tests whether taking a daily probiotic supplement called Limosilactobacillus reuteri LM1063 can improve sleep in healthy adults with poor sleep quality. Over 8 weeks, 80 participants will either take the probiotic or a placebo, and researchers will measure sleep using …

This Phase 3 trial tests whether the drug tasimelteon can help people with Delayed Sleep-Wake Phase Disorder (DSWPD) fall asleep earlier and sleep better. About 70 adults with DSWPD will receive either tasimelteon or a placebo daily. The study measures sleep onset and quality usi…

This study tests whether a structured exercise program can improve heart rate variability (a measure of heart health), reduce menopausal symptoms, and enhance sleep and quality of life in postmenopausal women aged 45 to 65. Forty women will either join a supervised 12-week exerci…

This study looks at whether being awake between 2:00 and 4:00 AM increases negative mood, poor decision-making, and suicidal thoughts. Adults who have had suicidal thoughts in the past six months will be tested in the lab and at home under different sleep conditions. The goal is …

This study looks at why people with damage to the hypothalamus or pituitary gland often have sleep problems. Researchers will compare 60 patients to healthy volunteers using sleep tests, hormone measurements, and brain scans. The goal is to find better ways to prevent and treat t…