Recurrent adult diffuse midline glioma, H3 K27-mutant

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Experimental drug triapine paired with radiation targets recurrent brain cancers

Disease control Recruiting now

This early-phase trial tests the safety and best dose of the drug triapine when given together with radiation therapy for people whose glioblastoma or astrocytoma has come back. Triapine works by blocking enzymes that cancer cells need to grow, while radiation kills cancer cells …

Matched conditions: RECURRENT ADULT DIFFUSE MIDLINE GLIOMA, H3 K27-MUTANT

Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Sep 04, 2026 00:00 UTC

Recurrent adult diffuse midline glioma, H3 K27-mutant

Get alerted when new Recurrent adult diffuse midline glioma, H3 K27-mutant trials appear

Experimental drug triapine paired with radiation targets recurrent brain cancers