PR-positive breast cancer
Clinical trials for PR-positive breast cancer explained in plain language.
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New drug cocktail aims to wipe out breast cancer before surgery
Disease control Recruiting nowThis phase 2 trial is testing whether giving a combination of three drugs—neratinib, an aromatase inhibitor (letrozole or anastrozole), and trastuzumab—before surgery can completely eliminate invasive breast cancer in postmenopausal women with ER-positive, HER2-positive breast ca…
Matched conditions: PR-POSITIVE BREAST CANCER
Phase 2 • Sponsor: Ruth O'Regan • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Can a platform trial match the right drug combo to each tumor?
Disease control Recruiting nowThis phase I/II platform trial tests several drug combinations, including evorpacept, trastuzumab deruxtecan, zanidatamab, tucatinib, and TTX-MC138, in people with advanced solid tumors, especially metastatic breast cancer. The goal is to find safe and promising regimens that cou…
Matched conditions: PR-POSITIVE BREAST CANCER
Phase 1/2 • Sponsor: QuantumLeap Healthcare Collaborative • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New app aims to help breast cancer patients stick with Long-Term treatment
Knowledge-focused Recruiting nowThis study is testing a new web and mobile app called SHIELD, designed to support women with hormone receptor-positive breast cancer who are on long-term hormone therapy. The goal is to see if the app is easy to use and helpful for managing treatment. About 30 women will particip…
Matched conditions: PR-POSITIVE BREAST CANCER
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC