Opioid use disorder, severe
Clinical trials for Opioid use disorder, severe explained in plain language.
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A new approach to bridge the gap: can personalized education boost opioid treatment uptake?
Disease control Recruiting nowThis pilot trial tests a program called TRTME, designed to help hospitalized patients with opioid use disorder begin medication treatment after discharge. The program includes personalized education to correct misconceptions about MOUD, feedback on individual overdose risk factor…
Matched conditions: OPIOID USE DISORDER, SEVERE
Sponsor: T. John Winhusen, PhD • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Can bringing addiction treatment to syringe programs save more lives?
Disease control Recruiting nowThis study tests whether offering buprenorphine treatment directly at syringe service programs (SSPs) helps more people start and stay on medication for opioid use disorder compared to referring them elsewhere. About 512 adults who use SSPs and have moderate to severe opioid use …
Matched conditions: OPIOID USE DISORDER, SEVERE
Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Could a diabetes drug help fight opioid addiction?
Disease control Recruiting nowThis study tests whether tirzepatide, a drug used for diabetes and weight loss, can help people with moderate to severe opioid use disorder stay in treatment and use fewer opioids when added to their regular buprenorphine medication. About 310 adults who recently started buprenor…
Matched conditions: OPIOID USE DISORDER, SEVERE
Phase 2 • Sponsor: T. John Winhusen, PhD • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Can a sound wave calm addiction? ultrasound targets the Brain's craving center
Disease control Recruiting nowThis trial tests whether a single session of low-intensity focused ultrasound aimed at a brain region linked to reward and craving can safely reduce substance cravings and prevent relapse in people with severe opioid or amphetamine use disorder. Sixty participants will receive th…
Matched conditions: OPIOID USE DISORDER, SEVERE
Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC