MITOCHONDRIAL DISEASE
Clinical trials for MITOCHONDRIAL DISEASE explained in plain language.
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Can an antioxidant boost brain health in mitochondrial disease?
Disease control Recruiting nowThis early-stage study tests whether N-acetylcysteine (NAC), an antioxidant, can safely increase brain glutathione levels in people with a specific mitochondrial DNA mutation (m.3243A>G). 18 adults with low brain glutathione will receive one of three daily doses (1800, 3600, or 5…
Matched conditions: MITOCHONDRIAL DISEASE
Phase: PHASE1 • Sponsor: Michio Hirano, MD • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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Tiny sensor could unlock muscle mysteries in rare disease
Knowledge-focused Recruiting nowThis study is testing a new, minimally invasive oxygen nanosensor to measure how well muscles use oxygen in people with mitochondrial myopathy (a muscle disease) and in healthy volunteers. The goal is to see if the sensor can reliably detect differences in muscle function, which …
Matched conditions: MITOCHONDRIAL DISEASE
Phase: PHASE1 • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated May 26, 2026 06:16 UTC
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New study aims to unlock secrets of infections in rare mitochondrial disease
Knowledge-focused Recruiting nowThis study looks at how infections affect people with mitochondrial disease, a rare genetic disorder that can cause muscle weakness and developmental delays. Researchers will collect blood samples and health data from 400 participants and their family members to find immune patte…
Matched conditions: MITOCHONDRIAL DISEASE
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated May 26, 2026 06:10 UTC