Metastatic colon cancer
Clinical trials for Metastatic colon cancer explained in plain language.
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Could a home workout program reshape the gut and tame chemo toxicity?
Disease control Recruiting nowThis trial tests whether a 12-week home-based exercise program can alter the gut microbiome in young adults (ages 18-50) with colorectal cancer who are undergoing chemotherapy. Participants are randomly assigned to either the exercise group or a waitlist control group. Researcher…
Matched conditions: METASTATIC COLON CANCER
Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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New t cell engager takes on tough colorectal cancer
Disease control Recruiting nowThis early-phase trial tests a new drug called CBI-1214 in 80 people with advanced colorectal cancer that has not responded to standard treatments. CBI-1214 is designed to connect the body's own immune T cells to cancer cells, helping the immune system attack the tumor. The main …
Matched conditions: METASTATIC COLON CANCER
Phase 1 • Sponsor: Cartography Biosciences • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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New drug cocktail targets cancers missing key gene
Disease control Recruiting nowThis study tests a new drug combination for people with metastatic solid tumors that lack a gene called MTAP. The drugs, BMS-986504 and pemetrexed, aim to stop cancer cells from growing. The trial will check safety and how well the combo works in 72 participants.
Matched conditions: METASTATIC COLON CANCER
Phase 1/2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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New smart drug TQB6411 targets two cancer proteins in early human trial
Disease control Recruiting nowThis Phase 1 trial tests TQB6411, an antibody-drug conjugate designed to bind to EGFR and c-Met proteins on tumor cells, blocking their growth signals and releasing a toxin to kill the cells. The study will enroll 216 adults with advanced malignant tumors to find the safest dose …
Matched conditions: METASTATIC COLON CANCER
Phase 1 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Fiber fix: new supplement aims to stop Chemo-Induced diarrhea
Symptom relief Recruiting nowThis study tests a high-fiber product called NBT-NM108 in 42 people with advanced colon cancer who are receiving a chemotherapy drug called irinotecan. The goal is to see if the supplement can reduce or prevent the severe diarrhea that often comes with this treatment. By helping …
Matched conditions: METASTATIC COLON CANCER
Phase 2 • Sponsor: Howard S. Hochster, MD • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC