Locally advanced (inoperable) or metastatic breast cancer
Clinical trials for Locally advanced (inoperable) or metastatic breast cancer explained in plain language.
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New combo aims to stall advanced breast cancer
Disease control OngoingThis study tests whether adding the experimental drug capivasertib to standard hormone therapy and CDK4/6 inhibitors can delay cancer growth in people with advanced HR+/HER2- breast cancer that cannot be removed by surgery or has spread. About 895 adults whose cancer has not resp…
Matched conditions: LOCALLY ADVANCED (INOPERABLE) OR METASTATIC BREAST CANCER
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New drug cocktail aims to stall breast cancer growth
Disease control OngoingThis phase 3 trial tests whether adding capivasertib to standard fulvestrant therapy can slow cancer growth in people with advanced HR+/HER2- breast cancer. About 818 participants whose cancer worsened after hormone therapy will receive either the combination or a placebo plus fu…
Matched conditions: LOCALLY ADVANCED (INOPERABLE) OR METASTATIC BREAST CANCER
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC