Hypoxic-ischemic encephalopathy (HIE)
Clinical trials for Hypoxic-ischemic encephalopathy (HIE) explained in plain language.
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Could caffeine help save newborn brains? major trial launches
Disease control Recruiting nowThis study tests whether giving caffeine to newborns with hypoxic ischemic encephalopathy (HIE) can reduce death or long-term disability. HIE is a brain injury caused by lack of oxygen around birth. The trial will enroll 830 full-term infants and give them either caffeine or a pl…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY (HIE)
Phase 3 • Sponsor: NICHD Global Network for Women's and Children's Health • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Cooling Newborns' brains: a lifesaving hope for Oxygen-Deprived babies?
Disease control Recruiting nowThis study tests if carefully cooling the body of newborns who suffered brain injury from lack of oxygen at birth can improve their chances of survival and long-term brain development. The treatment, called therapeutic hypothermia, is already used in some hospitals. This trial wi…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY (HIE)
Sponsor: National Children's Hospital, Vietnam • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Intensive brain training shows promise for kids with developmental delays
Knowledge-focused Recruiting nowThis study looks at how a 2-week, personalized therapy program helps children aged 4-12 with conditions like cerebral palsy, autism, or genetic disorders. Kids get about 2.5 hours of tailored therapy each day, focusing on skills like movement, attention, and communication. The go…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY (HIE)
Sponsor: Healing Hope International • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Could a Baby's genes cause HIE? new study investigates
Knowledge-focused Recruiting nowThis study offers genome sequencing to 25 newborns diagnosed with HIE (a severe brain condition from lack of oxygen at birth) who are receiving cooling therapy. Researchers want to find out how often genetic changes cause or contribute to HIE. The goal is to help doctors decide w…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY (HIE)
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC