DELETERIOUS PALB2 GENE MUTATION
Clinical trials for DELETERIOUS PALB2 GENE MUTATION explained in plain language.
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New combo therapy targets genetic breast cancers before surgery
Disease control OngoingThis study tests two drugs, niraparib and dostarlimab, given before surgery to people with BRCA or PALB2 gene mutations and early-stage breast cancer. The goal is to see if the treatment shrinks tumors and boosts immune activity. 62 participants are enrolled, and the study is act…
Matched conditions: DELETERIOUS PALB2 GENE MUTATION
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 26, 2026 03:17 UTC
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Can a less invasive surgery prevent ovarian cancer without harming sexual health?
Prevention OngoingThis study looks at two types of surgery to prevent ovarian cancer in women with certain gene mutations (like BRCA). One surgery removes both ovaries and fallopian tubes, while the other removes only the fallopian tubes first and delays ovary removal. The goal is to see which app…
Matched conditions: DELETERIOUS PALB2 GENE MUTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated May 22, 2026 13:53 UTC