Ddi (drug-drug interaction)

This early-stage study is testing whether a new investigational drug called ABP-671 can be safely taken together with the standard gout medication allopurinol. Twenty adults with gout who are already on a stable dose of allopurinol will take the drugs alone and together over thre…

Researchers are studying whether rifampicin or itraconazole change how the body handles befotertinib, an oral medicine for lung cancer. Thirty-six healthy volunteers take a single dose of befotertinib alone, then again after several days of rifampicin or itraconazole. The study m…

Researchers are studying whether rifampicin, an antibiotic, or itraconazole, an antifungal, change how the body handles vorolanib, an oral cancer drug. Thirty-six healthy volunteers take vorolanib alone, then again after several days of rifampicin or itraconazole. The trial measu…