Cervical intraepithelial neoplasia grade 1
Clinical trials for Cervical intraepithelial neoplasia grade 1 explained in plain language.
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DNA vaccine aims to clear HPV16 and reverse early cervical changes
Cure Not yet recruitingResearchers are testing a therapeutic DNA vaccine called pBI-4 in women with HPV16-positive grade 1 cervical intraepithelial neoplasia or persistent HPV16 infection. The vaccine is designed to train the immune system to target HPV16 proteins. Participants receive either the vacci…
Matched conditions: CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 1
Phase 1/2 • Sponsor: Chang Gung Memorial Hospital • Aim: Cure
Last updated Sep 16, 2026 00:00 UTC
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New cream after heat treatment may help women with HIV beat HPV
Disease control Not yet recruitingThis study tests whether a self-applied cream (5-fluorouracil) after a heat procedure (thermal ablation) can clear HPV better than a placebo cream in 140 women with HIV in Kenya. Participants will use the cream every two weeks for 24 weeks and be followed for 48 weeks total. The …
Matched conditions: CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 1
Phase 2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Turmeric compound tested as vaginal treatment for cervical precancer
Disease control Not yet recruitingThis phase 2 trial tests whether curcumin, the active compound in turmeric, can clear HPV and prevent precancerous cervical lesions from returning. About 200 women with low-grade or recently treated high-grade cervical precancer will insert curcumin or placebo capsules vaginally …
Matched conditions: CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 1
Phase 2 • Sponsor: Lisa Flowers • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC