Autoimmune liver disease
Clinical trials for Autoimmune liver disease explained in plain language.
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New drug aims to stop immune system from attacking transplanted livers
Disease control Recruiting nowThis early study tests whether siplizumab, given at the time of liver transplant, can safely prevent the immune system from attacking the new liver. Up to 8 adults with autoimmune hepatitis or primary sclerosing cholangitis will receive two doses. The main goal is to check for se…
Matched conditions: AUTOIMMUNE LIVER DISEASE
Phase 1 • Sponsor: Elizabeth C. Verna • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New blood test may sharpen diagnosis of autoimmune liver disease
Diagnosis Recruiting nowThis study evaluates whether a blood test measuring polyreactive immunoglobulin G (pIgG) can more accurately diagnose autoimmune hepatitis (AIH) and distinguish it from other liver conditions. Researchers will collect blood samples from 400 adults undergoing liver biopsy for susp…
Matched conditions: AUTOIMMUNE LIVER DISEASE
Sponsor: Hannover Medical School • Aim: Diagnosis
Last updated Jul 17, 2026 00:00 UTC
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MRI as a crystal ball for young liver disease patients?
Knowledge-focused Recruiting nowThis study follows 150 young people (ages 6-23) with autoimmune liver disease to see if MRI scans can predict how their condition will progress over the next decade. Participants will have MRI scans at the start and again at one and two years, while their clinical health is track…
Matched conditions: AUTOIMMUNE LIVER DISEASE
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Could a simple MRI spare young patients from invasive liver biopsies?
Knowledge-focused Recruiting nowThis study is testing whether MRI scans can accurately detect bile duct damage and liver scarring in young people aged 6 to 23 with autoimmune liver diseases like primary sclerosing cholangitis and autoimmune hepatitis. Researchers will compare MRI results with traditional liver …
Matched conditions: AUTOIMMUNE LIVER DISEASE
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC