AUTOIMMUNE DISEASE

This study is testing the safety of the immunotherapy drug nivolumab in people who have both advanced cancer and an autoimmune disease like lupus, rheumatoid arthritis, or Crohn's disease. It will enroll 300 adults to see how well they tolerate the treatment and to find the right…

This study is testing if the antiviral drug remdesivir can safely treat RSV (a common respiratory virus) in adults with weakened immune systems. Participants are people with cancer or autoimmune diseases who recently received treatments like stem cell transplants or specialized a…

This study is testing whether combining two existing drugs, rituximab and cyclosporine, is safe and more effective for treating membranous nephropathy, an autoimmune disease that damages the kidneys' filters. The goal is to reduce harmful protein loss in urine and achieve lasting…

This is the first human study of an experimental drug called GenSci136, which is being developed for autoimmune diseases. Researchers are testing it in 48 healthy adults to check if it's safe and to see how the body processes it. The study will measure drug levels in the blood an…

This study aims to learn more about bronchiectasis, a lung condition that causes repeated infections and breathing problems. Researchers will follow 900 patients and some of their family members over time, collecting health information and samples like blood and sputum. The goal …

This study is testing an educational tool designed to help melanoma patients who also have autoimmune diseases (like rheumatoid arthritis or Crohn's disease) understand their treatment options with immune checkpoint inhibitor drugs. Researchers want to see if the tool is easy to …

This study is testing whether genetic information can help doctors choose safer and more effective medications for their patients. Researchers will collect DNA samples from 1,200 adults receiving routine care at the University of Chicago Medical Center. They will track whether do…