Yolk sac tumor
MONDO:0005744A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum.
Also known as: endodermal sinus neoplasm, endodermal sinus tumor, hepatoid yolk sac tumor, yolk SAC tumor, malignant, yolk Sac neoplasm, yolk Sac tumor, yolk Sac tumor site unspecified, yolk Sac tumour site unspecified
2752 clinical trials for this condition and its sub-types, 12 tagged with Yolk sac tumor itself.
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Browse by category →Sub-types of Yolk sac tumor
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Ovarian yolk sac tumor 1 trial
4 sub-types
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Testicular yolk sac tumor 1 trial
10 sub-types
- Enteric pattern testicular yolk sac tumor 0 trials
- Polyvesicular vitelline pattern testicular yolk sac tumor 0 trials
- Reticular pattern testicular yolk sac tumor 0 trials
- Testicular yolk sac tumor, endodermal sinus pattern 0 trials
- Testicular yolk sac tumor, glandular-alveolar pattern 0 trials
- Testicular yolk sac tumor, hepatoid pattern 0 trials
- Testicular yolk sac tumor, macrocystic pattern 0 trials
- Testicular yolk sac tumor, myxomatous pattern 0 trials
- Testicular yolk sac tumor, papillary pattern 0 trials
- Testicular yolk sac tumor, solid pattern 0 trials
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Childhood endodermal sinus tumor 0 trials · 1 incl. sub-types
2 sub-types
- Central nervous system endodermal sinus tumor 0 trials · 1 incl. sub-types Sub-types →
- Childhood ovarian yolk sac tumor 0 trials
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Yolk sac tumor of central nervous system 0 trials · 1 incl. sub-types
1 sub-type
- Central nervous system endodermal sinus tumor 0 trials · 1 incl. sub-types Sub-types →
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Adult yolk sac tumor 0 trials
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Mediastinal yolk sac tumor 0 trials
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Vaginal yolk sac tumor 0 trials