Xanthomatosis

MONDO:0002615

A condition marked by the development of widespread xanthomas, yellow tumor-like structures filled with lipid deposits. Xanthomas can be found in a variety of tissues including the skin; tendons; joints of knees and elbows. Xanthomatosis is associated with disturbance of lipid metabolism and formation of foam cells.

Also known as: xanthomatosis, xanthomatosis (disease)

8 clinical trials for this condition and its sub-types, 2 tagged with Xanthomatosis itself.

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Where it sits in the disease tree

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Part of

↑ Lysosomal lipid storage disorder (192)

Sub-types of Xanthomatosis

Cerebrotendinous xanthomatosis 6 trials

Including sub-types (8) Tagged with Xanthomatosis (2)

Not yet recruiting 1 Completed 1

Could a Cholesterol-Lowering cream replace surgery for eyelid bumps?

Disease control Not yet recruiting

This study tests whether a cream containing simvastatin (a cholesterol-lowering drug) can safely shrink yellow cholesterol deposits on the eyelids, called xanthelasma. Thirty adults will apply either the active cream or a placebo nightly for 24 weeks, then everyone gets the activ…

Phase 2 • Sponsor: Klira Skin • Aim: Disease control

Last updated Jun 27, 2026 14:02 UTC

Xanthomatosis

Where it sits in the disease tree

Could a Cholesterol-Lowering cream replace surgery for eyelid bumps?