X-linked lymphoproliferative disease due to XIAP deficiency

MONDO:0010385

A condition of decreased or absent presence of baculoviral IAP repeat-containing protein 4. Deficiency of this protein is associated with X-linked lymphoproliferative syndrome 2.

Also known as: X-linked lymphoproliferative disease due to XIAP deficiency, X-linked lymphoproliferative syndrome type 2, XIAP deficiency, XIAP deficiency/XLPs, XLP2, lymphoproliferative syndrome, X-linked, 2, X-linked recessive, lymphoproliferative syndrome, X-linked, type 2, XIAP-related lymphoproliferative disease, X-linked

50 clinical trials for this condition and its sub-types, 4 tagged with X-linked lymphoproliferative disease due to XIAP deficiency itself.

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Where it sits in the disease tree

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↑ X-linked lymphoproliferative syndrome (11) ↑ X-linked recessive disease (10)

Including sub-types (50) Tagged with X-linked lymphoproliferative disease due to XIAP deficiency (4)

Trials to join now! 1 Not yet recruiting 1 Not yet finished but already full! 1 Completed 1

New drug combo shows promise for kids with rare immune disease

Disease control Completed

This study tested a drug called alemtuzumab (Campath) as a first treatment for children with hemophagocytic lymphohistiocytosis (HLH), a rare and life-threatening immune disorder. The goal was to see if it could help children survive until they could receive a stem cell transplan…

Phase 1/2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control

Last updated Jun 27, 2026 12:02 UTC

X-linked lymphoproliferative disease due to XIAP deficiency

Where it sits in the disease tree

New drug combo shows promise for kids with rare immune disease