Vulval Paget disease
MONDO:0002207An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterized by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.
Also known as: Paget disease of the vulva, Paget's disease of the vulva, Paget's disease of vulva, mammalian vulva Paget disease, vulva Paget's disease, vulval Paget's disease, vulvar Paget's disease
2850 clinical trials for this condition and its sub-types, 2 tagged with Vulval Paget disease itself.
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New light treatment offers hope for rare vulvar cancer
Disease control Recruiting nowThis study is testing a new device called PAGETEX that uses light therapy (photodynamic therapy) to treat a rare skin condition called vulvar Paget's disease. The disease often comes back after surgery, so researchers want to see if this light treatment can control it better. Abo…
Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New registry aims to unlock secrets of rare gynecologic condition
Knowledge-focused Recruiting nowThis study is creating a registry of 100 women with extramammary Paget's disease (EMPD) of the vulva or perianal area. Researchers will collect health information, tissue samples, and skin swabs to learn more about the disease and the bacteria living on affected skin. The goal is…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC