Von Willebrand disease (hereditary or acquired)
MONDO:0024574Hereditary or acquired coagulation disorder characterized by a qualitative or quantitative deficiency of the von Willebrand factor. The latter plays an important role in platelet adhesion. Signs and symptoms include bruises, nose bleeding, gum bleeding following a dental procedure, heavy menstrual bleeding, and gastrointestinal bleeding.
Also known as: VWD, Von Willebrand Disease, von Willebrand disorder, von Willebrand's disease, von Willebrand disease
49 clinical trials for this condition and its sub-types, 39 tagged with Von Willebrand disease (hereditary or acquired) itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Von Willebrand disease (hereditary or acquired)
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Hereditary von Willebrand disease 18 trials · 29 incl. sub-types
5 sub-types
- Von Willebrand disease 3 9 trials
- Von Willebrand disease 2 4 trials · 5 incl. sub-types Sub-types →
- Von Willebrand disease 1 3 trials
- Von Willebrand disease, X-linked form 0 trials
- Platelet-type von Willebrand disease 0 trials
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Acquired von willebrand syndrome 3 trials
Most studied deeper sub-types
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New clotting factor combo aims to tame von willebrand bleeding
Disease control OngoingThis study looks at how well Eqwilate, a concentrated mix of two clotting proteins (VWF and FVIII), controls bleeding in people with von Willebrand disease. It includes patients aged 6 and older who use Eqwilate on demand, before surgery, or as regular prevention. Researchers tra…
Sponsor: Octapharma • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Trial for bleeding disorder drug in toddlers pulled before it started
Disease control CancelledThis study was designed to test how FANHDI, a clotting factor concentrate, works in children under 6 with severe von Willebrand disease (types 2 or 3). The goal was to measure how the drug moves through the body and how well it controls bleeding. However, the trial was withdrawn …
Phase 4 • Sponsor: Grifols Therapeutics LLC • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Family history questions may improve bleeding disorder detection in kids
Knowledge-focused OngoingThis study looks at whether adding simple family history questions to a standard bleeding questionnaire can better identify children who truly have mild bleeding disorders. Researchers will review data from 1,000 children seen at a clinic since 2019. The goal is to see if this co…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC