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Ventricular septal defect
MONDO:0002070The presence of a defect (opening) in the septum that separates the two ventricles of the heart. It can be congenital or acquired.
Also known as: VSD, interventricular communication, interventricular septal defect, ventricular septal defect, ventricular septal defect (disease), heart septal defects, ventricular, ventricular septal defects
99 clinical trials for this condition and its sub-types, 24 tagged with Ventricular septal defect itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Ventricular septal defect
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Double outlet right ventricle 2 trials · 3 incl. sub-types
5 sub-types
- Double outlet right ventricle with subaortic or doubly committed ventricular septal defect with pulmonary stenosis 1 trial
- Double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy 0 trials
- Double outlet right ventricle with non-committed subpulmonary ventricular septal defect 0 trials
- Double outlet right ventricle with subaortic or doubly committed ventricular septal defect 0 trials
- Double outlet right ventricle with subpulmonary ventricular septal defect 0 trials
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Ventricular septal defect 1 0 trials
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Ventricular septal defect 2 0 trials
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Ventricular septal defect 3 0 trials
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Heart hole device under the microscope: does it hold up?
Disease control OngoingThis study follows 50 people who have a hole in the wall between their heart's lower chambers (a perimembranous VSD). They received a special device to close the hole without open-heart surgery. Researchers are checking if the device stays in place and closes the hole properly, a…
Sponsor: Occlutech International AB • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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A crystal ball for heart defects: can a new model predict which children heal without surgery?
Knowledge-focused CancelledThis study looks at children diagnosed with a ventricular septal defect (a hole in the heart) to understand if and when the hole might close without treatment. Researchers will follow children from birth to age 14 and use echocardiography to track the defect. The goal is to build…
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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AI reads heart scans to predict which children will develop serious complications
Knowledge-focused OngoingThis study explores whether artificial intelligence can predict which children with a type of heart hole (perimembranous ventricular septal defect) will later develop complications like valve problems or blockages. Researchers will analyze past echocardiogram reports and medical …
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC