Ventricular septal defect
MONDO:0002070The presence of a defect (opening) in the septum that separates the two ventricles of the heart. It can be congenital or acquired.
Also known as: VSD, interventricular communication, interventricular septal defect, ventricular septal defect, ventricular septal defect (disease), heart septal defects, ventricular, ventricular septal defects
97 clinical trials for this condition and its sub-types, 24 tagged with Ventricular septal defect itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Ventricular septal defect
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Double outlet right ventricle 2 trials · 3 incl. sub-types
5 sub-types
- Double outlet right ventricle with subaortic or doubly committed ventricular septal defect with pulmonary stenosis 1 trial
- Double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy 0 trials
- Double outlet right ventricle with non-committed subpulmonary ventricular septal defect 0 trials
- Double outlet right ventricle with subaortic or doubly committed ventricular septal defect 0 trials
- Double outlet right ventricle with subpulmonary ventricular septal defect 0 trials
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Ventricular septal defect 1 0 trials
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Ventricular septal defect 2 0 trials
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Ventricular septal defect 3 0 trials
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Less invasive heart repair: device closure offers hope for children with VSD
Disease control Not yet recruitingThis study looks at how well a device can close a common heart hole called a ventricular septal defect (VSD) in children aged 6 months to 18 years. Instead of open-heart surgery, doctors use a small tube to place a device that plugs the hole. The goal is to see if this method is …
Sponsor: Assiut University • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Can a simple heart pump save lives after a heart attack complication?
Disease control Not yet recruitingThis study tests whether inserting a heart pump (IABP) early, before severe shock develops, can reduce deaths in patients who develop a hole in the heart after a heart attack. The trial will enroll 100 patients across 5 centers, randomly assigning half to receive the pump within …
Sponsor: Qilu Hospital of Shandong University • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Can an ultrasound replace a catheter for Kids' heart surgery planning?
Diagnosis Not yet recruitingThis study looks at 115 children aged 6 months to 5 years who have a hole in the heart (VSD) and need surgery. Doctors want to see if an ultrasound probe placed in the food pipe (TEE) can measure heart pressure as accurately as the standard method using a thin tube (catheter) ins…
Sponsor: Ain Shams University • Aim: Diagnosis
Last updated Jun 27, 2026 14:01 UTC
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Could clear priming reduce inflammation after infant heart surgery?
Symptom relief Not yet recruitingThis study looks at whether using clear, non-blood fluids to fill the heart-lung machine during surgery can reduce inflammation in infants having a hole in the heart repaired. Sixty babies aged 1 to 18 months will be enrolled. Researchers will measure inflammation markers and rec…
Sponsor: Seattle Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Heart surgery may help small kids grow: study to track 58 infants
Knowledge-focused Not yet recruitingThis study looks at whether children who had surgery to close a large hole in their heart (called a VSD) will catch up in growth. Researchers will measure weight, height, and BMI before and after the procedure in 58 children aged 1 month to 2 years. The goal is to see how long it…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC