Upper aerodigestive tract neoplasm

This study tests whether a special spa therapy can improve skin-related quality of life in people who have skin hardening (fibrosis) after radiation for breast or head/neck cancer. About 110 adults who finished radiation at least 6 months ago will be randomly assigned to receive …

This study looks at whether adding three extra support visits after surgery can lower anxiety and improve quality of life for people with head and neck cancers. About 60 patients will take part. The goal is to see if more follow-up care helps patients cope better after their oper…

This study tests whether a structured physical activity program can reduce how much time head and neck cancer patients spend sitting or lying down. Researchers will track 96 patients over 18 months, measuring their movement, quality of life, and fatigue. Half the patients will fo…

This study tests whether specially adapted beauty sessions (onco-esthetics) can help people with head and neck cancer feel better about their changed appearance after treatment. Fifty-five patients will receive three sessions, and researchers will measure how their self-image cha…

This study collects blood, tumor, and other tissue samples from up to 1,250 people with head and neck, lung, or gastrointestinal cancers. Researchers want to understand how the immune system changes during cancer treatments, especially immunotherapies. Participants donate samples…

This study follows 50 adults who have had head and neck cancer and now use custom dental prostheses. Researchers will measure how well they chew food and how their quality of life changes over time. The goal is to understand the real-world benefits of these prostheses for cancer …

This study is looking for certain cells in the blood of people with 9 types of advanced cancers that have spread. Researchers will take one blood sample from each of 450 participants before they start a new treatment. They will use two different lab methods to see if they can fin…

This study aims to find a unique chemical pattern (metabolomic signature) in blood, urine, and tumor samples from 250 people with upper aerodigestive tract cancers. By analyzing these samples before and after treatment, researchers hope to improve early detection, predict treatme…

This study is testing whether measuring circulating tumor DNA (ctDNA) in the blood can predict if cancer will come back after radiation therapy. Researchers will collect blood samples from 188 patients with advanced head and neck cancer before, during, and after treatment. The go…