Undifferentiated ovarian carcinoma
MONDO:0006477An aggressive carcinoma arising from the ovary. Most patients present with advanced disease. Microscopically, it is characterized by significant cytologic atypia, increased mitotic activity, and necrosis. The prognosis is usually poor.
Also known as: anaplastic carcinoma of ovary, anaplastic carcinoma of the ovary, anaplastic ovarian carcinoma, ovarian undifferentiated carcinoma, ovary undifferentiated carcinoma, undifferentiated carcinoma of ovary, undifferentiated carcinoma of the ovary, undifferentiated ovarian cancer
2862 clinical trials for this condition and its sub-types, 13 tagged with Undifferentiated ovarian carcinoma itself.
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Major trial tests if abdominal chemo beats IV for tough cancers
Disease control CompletedThis large Phase III trial tested whether adding the drug bevacizumab to chemotherapy works better when the chemo is given into a vein (IV) or directly into the belly (IP). It involved 1560 people with advanced ovarian, fallopian tube, or peritoneal cancers. The goal was to see w…
Phase 3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Diabetes drug metformin may boost chemo for ovarian cancer
Disease control CompletedThis phase II trial tested whether adding metformin, a common diabetes drug, to standard chemotherapy could help control advanced ovarian, fallopian tube, or primary peritoneal cancer. 111 participants received either metformin or a placebo alongside chemotherapy, followed by mai…
Phase 2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could a custom vaccine help fight ovarian cancer?
Disease control CompletedThis early-phase trial tested a personalized vaccine made from a patient's own immune cells to see if it is safe for people with advanced ovarian, fallopian tube, or peritoneal cancer. Nineteen participants who had already undergone surgery and chemotherapy received the vaccine. …
Early phase 1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC