Undifferentiated carcinoma of esophagus

MONDO:0018481

An esophageal carcinoma characterized by the absence of microscopic features of squamous differentiation. However, there is immunohistochemical evidence of squamous differentiation.

Also known as: esophageal undifferentiated carcinoma, esophagus undifferentiated carcinoma, oesophagus undifferentiated carcinoma, undifferentiated esophageal cancer, undifferentiated esophageal carcinoma

2877 clinical trials for this condition and its sub-types, 1 tagged with Undifferentiated carcinoma of esophagus itself.

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Where it sits in the disease tree

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Part of

↑ Esophageal squamous cell carcinoma (307) ↑ Undifferentiated carcinoma (80)

Including sub-types (2877) Tagged with Undifferentiated carcinoma of esophagus (1)

Not yet finished but already full! 1

Immunotherapy duo takes on rare tumors

Disease control Ongoing

This phase 2 trial is testing a combination of two immunotherapy drugs, nivolumab and ipilimumab, in 798 people with over 50 types of rare cancers. The goal is to see if these drugs can shrink tumors by helping the immune system attack cancer cells. Participants receive the drugs…

Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Jun 27, 2026 14:00 UTC

Undifferentiated carcinoma of esophagus

Where it sits in the disease tree

Immunotherapy duo takes on rare tumors