Treatment-refractory schizophrenia
MONDO:0005414Schizophrenia which does not respond to commonly used treatments.
Also known as: TRS, refractory schizophrenia, treatment-refractory schizophrenia
97 clinical trials for this condition and its sub-types, 25 tagged with Treatment-refractory schizophrenia itself.
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New talk therapy aims to boost recovery in Treatment-Resistant mental illness
Disease control OngoingThis study tests whether adding a new recovery-focused psychotherapy program (RECOVERYTRSGR or RECOVERYTRSBDGR) to standard medication can improve thinking, symptoms, and daily function in people with treatment-resistant schizophrenia or bipolar disorder. About 84 adults aged 18–…
Phase 4 • Sponsor: Dr. Stavroula Rakitzi • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Sound waves aimed at brain may quiet schizophrenia symptoms
Symptom relief PausedThis pilot study tests whether low-intensity focused ultrasound, guided by MRI, can safely and feasibly target a deep brain region (the thalamus) in people with treatment-resistant schizophrenia. Only 3 participants were planned, and the study is currently suspended. The goal is …
Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC