Tongue cancer
MONDO:0004631A malignant neoplasm affecting the tongue. The vast majority of cases are carcinomas.
Also known as: cancer of tongue, malignant neoplasm of tongue, malignant tongue neoplasm, malignant tongue tumor, malignant tongue tumour, malignant tumor of the tongue, malignant tumor of tongue, malignant tumour of the tongue
2985 clinical trials for this condition and its sub-types, 26 tagged with Tongue cancer itself.
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Sub-types of Tongue cancer
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Tongue squamous cell carcinoma 9 trials · 13 incl. sub-types
1 sub-type
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Tongue carcinoma 4 trials
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Can less radiation beat throat cancer without chemo?
Disease control CompletedThis study tested whether a lower dose of radiation therapy, with or without the chemotherapy drug cisplatin, can effectively treat advanced oropharyngeal (throat) cancer in patients who are non-smokers. The trial enrolled 316 people with p16-positive cancer, a type linked to HPV…
Phase 2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New combo therapy shows promise for tough head and neck cancers
Disease control CompletedThis phase II trial tested whether adding sorafenib to cetuximab works better than cetuximab alone for patients with advanced head and neck cancer that has come back or spread. Fifty-five adults with various types of head and neck cancer took part. The study measured how long pat…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Radiation after surgery may keep early oral cancer at bay
Disease control CompletedThis study looked at whether giving radiation therapy after surgery can prevent early-stage oral cancer from coming back. It included 392 patients with tumors at least 5mm thick. Half received radiation, half were just watched. The main goal was to see if radiation reduced local …
Sponsor: Tata Memorial Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Tiny radioactive seeds tested again for returning cancers
Disease control CompletedThis study tested whether a second round of treatment with tiny radioactive seeds (DaRT) could safely shrink or control skin, mouth, or soft tissue cancers that came back after the first treatment. Only 2 people took part, and researchers measured tumor response and side effects.…
Sponsor: Alpha Tau Medical LTD. • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New combo therapy aims to stop head and neck cancer return
Disease control CompletedThis phase II trial tested whether adding the targeted drug cetuximab to standard chemotherapy and radiation could help prevent head and neck cancer from coming back after surgery. The study enrolled 53 patients with certain high-risk features. The main goal was to see how many p…
Phase 2 • Sponsor: Centre Antoine Lacassagne • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Can a special diet before surgery prevent infections in head and neck cancer patients?
Disease control CompletedThis phase 3 trial tested whether giving a special nutritional supplement (immunonutrition) before and after surgery could reduce infections in 311 patients with head and neck cancer. Participants were randomly assigned to one of three nutrition regimens. The main goal was to see…
Phase 3 • Sponsor: Centre Antoine Lacassagne • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Two ways to rebuild a tongue: which one leaves patients better off?
Symptom relief CompletedResearchers compare two surgical techniques for rebuilding the tongue after cancer removal: the submental island pedicled flap, taken from under the chin, and the radial forearm free flap, taken from the arm. Twenty-eight adults with tongue cancer that requires partial or total r…
Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Sep 17, 2026 00:00 UTC
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Why do Non-Smokers get head and neck cancer? scientists probe tumor DNA
Knowledge-focused CompletedResearchers are studying blood and tumor tissue from people with squamous cell cancer of the larynx, pharynx, or oral cavity who have no history of smoking, heavy drinking, or workplace exposure to substances like asbestos or wood dust. The goal is to learn how DNA changes and bi…
Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC