Thyroid gland disorder
MONDO:0003240A disease involving the thyroid gland.
Also known as: disease of thyroid gland, disease or disorder of thyroid gland, disorder of thyroid gland, thyroid disease, thyroid gland disease, thyroid gland disease or disorder, thyroid gland diseases, thyroid gland disorder
538 clinical trials for this condition and its sub-types, 96 tagged with Thyroid gland disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Thyroid gland disorder
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Thyroid tumor 36 trials · 366 incl. sub-types
5 sub-types
- Thyroid cancer 166 trials · 328 incl. sub-types Sub-types →
- Benign thyroid gland neoplasm 21 trials · 26 incl. sub-types Sub-types →
- TSH producing pituitary tumor 0 trials · 2 incl. sub-types Sub-types →
- Familial thyroglossal duct cyst 2 trials
- Thyroid hyalinizing trabecular adenoma 0 trials
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Goiter 12 trials · 102 incl. sub-types
7 sub-types
- Toxic diffuse goiter 0 trials · 53 incl. sub-types Sub-types →
- Nodular goiter 36 trials · 43 incl. sub-types Sub-types →
- Endemic goiter 4 trials
- Nontoxic goiter 1 trial
- Substernal goiter 1 trial
- Dyshormonogenic goiter 0 trials
- Lingual goiter 0 trials
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Hyperthyroidism 27 trials · 70 incl. sub-types
10 sub-types
- Primary hyperthyroidism 1 trial · 59 incl. sub-types Sub-types →
- Toxic diffuse goiter 0 trials · 53 incl. sub-types Sub-types →
- Generalized resistance to thyroid hormone 1 trial · 2 incl. sub-types Sub-types →
- Secondary hyperthyroidism 0 trials · 2 incl. sub-types Sub-types →
- Thyrotoxicosis 2 trials Sub-types →
- Familial gestational hyperthyroidism 0 trials
- Familial hyperthyroidism due to mutations in TSH receptor 0 trials
- Hyperthyroxinemia, familial dysalbuminemic 0 trials
- Selective pituitary resistance to thyroid hormone 0 trials
- Thyroid crisis 0 trials
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Thyroiditis 1 trial · 62 incl. sub-types
3 sub-types
- Autoimmune thyroid disease 8 trials · 62 incl. sub-types Sub-types →
- Acute thyroiditis 0 trials · 2 incl. sub-types Sub-types →
- Suppurative thyroiditis 0 trials
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Hypothyroidism 48 trials · 60 incl. sub-types
6 sub-types
- Congenital hypothyroidism 10 trials · 14 incl. sub-types Sub-types →
- Postsurgical hypothyroidism 1 trial
- Iodine hypothyroidism 0 trials
- Myxedema 0 trials
- Myxedema coma 0 trials
- Myxedema heart disease 0 trials
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Inherited thyroid metabolism disease 0 trials · 8 incl. sub-types
2 sub-types
- Familial thyroid dyshormonogenesis 1 trial · 4 incl. sub-types Sub-types →
- Thyroid hormone resistance syndrome 3 trials · 4 incl. sub-types Sub-types →
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C-cell hyperplasia 0 trials
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Atrophy of thyroid 0 trials
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Euthyroid sick syndrome 0 trials
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Hyperthyroxinemia 0 trials
3 sub-types
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Thyrocalcitonin secretion disease 0 trials
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Thyroid malformation 0 trials
Most studied deeper sub-types
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Experimental combo targets deadly thyroid cancer
Disease control Stopped earlyThis phase 2 trial tested whether the immunotherapy drug pembrolizumab, given after radiation therapy, could help control anaplastic thyroid cancer that is still in the neck. Only 6 patients were enrolled before the study was stopped early. The goal was to see how long patients l…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New Hand-Held imager aims to prevent accidental parathyroid damage in thyroid surgery
Diagnosis Stopped earlyThis early study tested a hand-held imaging device to help surgeons identify parathyroid glands during thyroid surgery. The parathyroid glands are small and hard to see, and if accidentally removed or damaged, can cause low calcium levels and other complications. The device uses …
Phase 1 • Sponsor: OPTOSURGICAL, LLC • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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Diabetes drug may ease thyroid treatment side effects
Symptom relief Stopped earlyThis small pilot study tested whether metformin, a common diabetes drug, could reduce side effects like dry mouth and taste changes from radioactive iodine treatment in people with thyroid cancer. Only 13 people took part, and the study was stopped early. The goal was to see if m…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Brain fatigue after thyroid disease: immune system may be to blame
Knowledge-focused Stopped earlyThis study investigates why some people with Graves' disease continue to feel mentally fatigued even after their thyroid levels return to normal. Researchers will compare blood and spinal fluid from 180 participants—60 with mental fatigue, 60 without, and 60 healthy controls—to f…
Sponsor: Vastra Gotaland Region • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC