Thrombotic thrombocytopenic purpura

MONDO:0018896

Thrombotic thrombocytopenic purpura (TTP) is an aggressive and life-threatening form of thrombotic microangiopathy (TMA) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of congenital TTP and acquired TTP.

Also known as: Moschcowitz disease, Moschowitz disease, TTP

32 clinical trials for this condition and its sub-types, 15 tagged with Thrombotic thrombocytopenic purpura itself.

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↑ Thrombocytopenic purpura (116) ↑ Thrombophilia (75)

Sub-types of Thrombotic thrombocytopenic purpura

Acquired thrombotic thrombocytopenic purpura 13 trials
Congenital thrombotic thrombocytopenic purpura 5 trials

Including sub-types (32) Tagged with Thrombotic thrombocytopenic purpura (15)

Trials to join now! 5 Not yet recruiting 1 Not yet finished but already full! 4 Completed 5

New hope for rare blood disorder: study reviews real-world use of enzyme therapy

Knowledge-focused Not yet recruiting

This study looks back at medical records of people with congenital thrombotic thrombocytopenic purpura (cTTP), a rare inherited blood disorder that causes dangerous blood clots. Participants received a manufactured version of the missing ADAMTS13 enzyme through an early access pr…

Sponsor: Takeda • Aim: Knowledge-focused

Last updated Aug 30, 2026 00:00 UTC

Thrombotic thrombocytopenic purpura

Where it sits in the disease tree

New hope for rare blood disorder: study reviews real-world use of enzyme therapy