Thrombotic microangiopathy
MONDO:0019737The syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation.
154 clinical trials for this condition and its sub-types, 26 tagged with Thrombotic microangiopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Thrombotic microangiopathy
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Thrombocytopenic purpura 8 trials · 116 incl. sub-types
2 sub-types
- Autoimmune thrombocytopenic purpura 95 trials
- Thrombotic thrombocytopenic purpura 15 trials · 20 incl. sub-types Sub-types →
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Atypical hemolytic-uremic syndrome 19 trials
4 sub-types
Most studied deeper sub-types
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New hope for rare blood disorder: experimental drug TGD001 enters human trials
Disease control Not yet recruitingThis early-phase trial tests a new drug called TGD001 in about 70 adults with acute episodes of immune-mediated thrombotic thrombocytopenic purpura (iTTP) or related blood clotting conditions. The main goal is to check the drug's safety and how the body processes it, while also l…
Phase 1/2 • Sponsor: TargED Biopharmaceuticals B.V. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New study aims to uncover hidden danger in stem cell transplants
Knowledge-focused Not yet recruitingThis study will follow 85 adults receiving stem cell transplants to track a serious but often missed complication called TA-TMA. Researchers want to find out how common it is and how it affects survival. Participants will provide blood samples and have standard follow-up care.
Sponsor: Manuel Ricardo Espinoza-Gutarra • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Could interferon be a hidden trigger of blood clot damage after transplant?
Knowledge-focused Not yet recruitingThis study investigates how interferon and complement proteins contribute to thrombotic microangiopathy (TMA), a serious condition involving small blood clots and organ damage that can occur after stem cell transplants. Researchers will measure interferon levels, complement activ…
Sponsor: Sofie Dhaese • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC