Testicular seminoma
MONDO:0003669A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma.
Also known as: seminoma of testis, seminoma of the testis, seminomatous germ cell tumor of testis, seminomatous germ cell tumour of testis, testicular seminoma, testicular seminoma (disease), testicular seminoma Pure, testicular seminomatous germ cell tumor
2751 clinical trials for this condition and its sub-types, 8 tagged with Testicular seminoma itself.
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Sub-types of Testicular seminoma
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Spermatocytic seminoma 0 trials
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Tubular variant testicular seminoma 0 trials
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Can some seminoma patients safely skip heavier treatment?
Disease control Recruiting nowThis phase 2 trial explores whether some people with stage II seminoma, a type of testicular cancer, can receive less intensive treatment after surgery. All participants first receive one cycle of EP chemotherapy. Those whose PET scan is negative are then randomly assigned to eit…
Phase 2 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Major trial tests gentler chemo for germ cell tumors
Disease control Recruiting nowThis phase 3 trial studies two approaches for germ cell tumors. For low-risk patients whose tumor has been removed, doctors will monitor them closely instead of giving chemotherapy. For standard-risk patients whose cancer has spread, the trial compares two chemotherapy drugs—carb…
Phase 3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Robotic surgery may replace chemo for testicular cancer
Disease control Recruiting nowThis study tests whether robotic surgery can be the first treatment for stage IIA/B testicular seminoma, instead of chemotherapy or radiation. The surgery removes lymph nodes in the abdomen using a robot. The goal is to see if it prevents cancer from coming back. The trial will e…
Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Can a simple injection save your hearing during cancer treatment?
Symptom relief Recruiting nowThis early-stage trial tests whether adding Pedmark to standard cisplatin chemotherapy can prevent hearing loss in men with metastatic testicular cancer. About 80% of patients currently develop hearing damage from cisplatin. Pedmark works by neutralizing harmful molecules that ca…
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Blood test aims to spot hidden cancer cells in 9 tumor types
Knowledge-focused Recruiting nowThis study is looking for certain cells in the blood of people with 9 types of advanced cancers that have spread. Researchers will take one blood sample from each of 450 participants before they start a new treatment. They will use two different lab methods to see if they can fin…
Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC